Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.33 |
| ▸ | ACP1 | P24666 | 3/20 | 0.33 |
| ▸ | CDC25B | P30305 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3239425 | 0.93 | MMP2 (0.40) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL3246348 | 0.93 | MMP2 (0.40) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL3239913 | 0.93 | MMP2 (0.40) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL4656839 | 0.83 | MMP9 (0.34) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL3750812 | 0.80 | — | — | |
| SCHEMBL3237199 | 0.76 | AKT1 (0.32) | MMP9 | |
| SCHEMBL17307320 | 0.68 | SIRT2 (0.38) | KMT2AMEN1PTPN1ACP1CDC25B | |
| SCHEMBL3239326 | 0.66 | LMNA (0.30) | — | |
| SCHEMBL3743046 | 0.64 | TDP1 (0.35) | ALDH1A1KMT2ACYP1A2CYP3A4HPGD | |
| SCHEMBL4652250 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | GIVAUDAN SA (CH) | 2010-11-18 | — | — | US | disclosed |
| EP-1996569-B1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2010-07-28 | — | — | EP | disclosed |
| EP-1996569-B1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2010-07-28 | — | — | EP | disclosed |
| EP-1996569-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | Givaudan SA (CH) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007107023-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-09-27 | — | — | WO | disclosed |
| WO-2007107023-A1 | FLAVORANT AND FRAGRANCE COMPOUNDS | GIVAUDAN SA (CH) | 2007-09-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100291275-A1 | Flavorant and Fragrance Furan-2(5H)-One Compounds | TAS2R5, TAS2R1, TAS1R1 | ALDH1A1 106/4885KMT2A 2847/4885CYP1A2 289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.