Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2537035 | 0.79 | SMN1; SMN2 (0.33) | ALDH1A1LMNAHSD17B10GPR119TSHR | |
| SCHEMBL7120130 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SOAT1LMNAHSD17B10TSHR | |
| SCHEMBL8308690 | 0.76 | ALDH1A1 (0.48) | ALDH1A1SOAT1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL22898114 | 0.73 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL4498700 | 0.71 | GPR119 (0.40) | ALDH1A1LMNAGPR119 | |
| SCHEMBL16908082 | 0.71 | ALDH1A1 (0.42) | ALDH1A1GPR119SMN1; SMN2 | |
| SCHEMBL8311343 | 0.69 | ALDH1A1 (0.44) | ALDH1A1SOAT1LMNAHSD17B10SMN1; SMN2 | |
| SCHEMBL24517115 | 0.69 | KMT2A (0.30) | — | |
| SCHEMBL1810872 | 0.67 | SMN1; SMN2 (0.36) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7878595 | 0.67 | ALDH1A1 (0.41) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2185563-B1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER IP GMBH (DE) | 2015-08-19 | — | — | EP | disclosed |
| EP-2185563-A1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | Bayer CropScience AG (DE) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009015801-A1 | OXASPIROCYCLIC SPIRO-SUBSTITUTED TETRAMIC AND TETRONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2009-02-05 | — | — | WO | disclosed |
| EP-2020413-A1 | Oxaspirocyclical spiro-substituted tetram and tetron acid derivatives | Bayer CropScience AG (DE) | 2009-02-04 | — | — | EP | disclosed |