Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8038799 | 0.73 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8485908 | 0.69 | PSMB8 (0.42) | PSMB8ALDH1A1TSHRHTTLMNA | |
| SCHEMBL29561649 | 0.69 | — | — | |
| SCHEMBL5474087 | 0.69 | ALDH1A1 (0.41) | PSMB8MALT1ALDH1A1KDM4ETSHR | |
| SCHEMBL18905972 | 0.68 | THRB (0.31) | THRB | |
| SCHEMBL25156246 | 0.67 | PSMB8 (0.44) | PSMB8MALT1ALDH1A1KDM4ETSHR | |
| SCHEMBL2748847 | 0.67 | PSMB8 (0.44) | PSMB8ALDH1A1KDM4ETSHRGAA | |
| SCHEMBL9088304 | 0.67 | TRPV4 (0.35) | PSMB8SMN1; SMN2 | |
| SCHEMBL9666635 | 0.67 | BAZ1A (0.33) | PSMB8NSD2ALDH1A1KDM4E | |
| SCHEMBL20265769 | 0.65 | MAPT (0.34) | ALDH1A1HTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | claimed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | claimed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | claimed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | claimed |
| JP-1090176-A | — | — | None | — | — | JP | disclosed |
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENT -RUN FÜR GESUNDHEIT UND (DE) | 2015-02-05 | — | — | US | disclosed |
| EP-2736331-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8481810-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2013-07-09 | — | — | US | disclosed |
| WO-2013014245-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) | 2013-01-31 | — | — | WO | disclosed |
| US-7838732-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2010-11-23 | — | — | US | disclosed |
| WO-2009095098-A2 | USE OF BENZOTHIADIAZOLES | RWTH AACHEN (DE) | 2009-08-06 | — | — | WO | disclosed |
| US-7361806-B2 | Transgenic plants expressing a cellulase | SYNGENTA PARTICIPATIONS AG (CH) | 2008-04-22 | — | — | US | disclosed |
| US-5229384-A | Microbiocides | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |
| US-5190928-A | Benzo-1,2,3-thiadiazoles | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| EP-0313512-B1 | BENZOTHIADIAZOLES AND THEIR USE IN PROCESSES AND COMPOSITIONS AGAINST PLANT DISEASES | CIBA-GEIGY AG (CH) | 1992-11-25 | — | — | EP | disclosed |
| EP-0502473-A1 | Microbicidal benzo-1,2,3-thiadiazole derivatives | CIBA-GEIGY AG (CH) | 1992-09-09 | — | — | EP | disclosed |
| EP-0420803-A2 | Benzo-1,2,3-thiadiazole derivatives and their use for protecting plants against diseases | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4931581-A | CHEMICAL INTERMEDIATES FOR 1,2,3-BENZOTHIADIAZOLE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1990-06-05 | — | — | US | disclosed |
| EP-0332104-A2 | Chemically regulatable DNA sequences and genes and uses thereof | CIBA-GEIGY AG (CH) | 1989-09-13 | — | — | EP | disclosed |
| EP-0313512-A2 | Benzothiadiazoles and their use in processes and compositions against plant diseases | CIBA-GEIGY AG (CH) | 1989-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150038333-A1 | PLANT PROTECTIVE COMPOSITION CONTAINING ALPHA-HYDROXY ACIDS | HAO1, HAAO, HAO2 | PSMB8 886/4885MALT1 4106/4885NSD2 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.