Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21802278 | 0.81 | TYR (0.65) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL21225589 | 0.80 | CA3 (0.48) | TYR | |
| SCHEMBL933119 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL69697 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL30513627 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL3749696 | 0.80 | TYR (0.58) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL2361005 | 0.78 | TYR (0.56) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL21802276 | 0.78 | TYR (0.61) | TYRALOX5MEN1MAPTKMT2A | |
| SCHEMBL8698637 | 0.77 | TYR (0.54) | TYRALOX5MEN1KMT2ACYP3A4 | |
| SCHEMBL3934466 | 0.77 | TYR (0.54) | TYRALOX5MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795163-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | CHECKMATE THERAPEUTICS INC. | 2023-10-24 | — | — | US | disclosed |
| US-20230270692-A1 | COMPOUNDS FOR CHRONIC DISORDERS | PILLAI UNIVERSAL LLC | 2023-08-31 | — | — | US | disclosed |
| US-20230270692-A1 | COMPOUNDS FOR CHRONIC DISORDERS | PILLAI UNIVERSAL LLC | 2023-08-31 | — | — | US | disclosed |
| US-11078195-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | CHECKMATE THERAPEUTICS INC. | 2021-08-03 | — | — | US | disclosed |
| US-20210171513-A1 | NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2021-06-10 | — | — | US | disclosed |
| CN-108779104-B | Novel compounds for inhibiting nicotinamide phosphoribosyltransferase and compositions containing same | 将军治疗有限公司 | 2021-04-13 | — | — | CN | disclosed |
| US-20200247795-A1 | NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME | CHECKMATE THERAPEUTICS INC. (KR) | 2020-08-06 | — | — | US | disclosed |
| EP-3431472-A2 | NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME | Industry-Academic Cooperation Foundation Yonsei University (KR) | 2019-01-23 | — | — | EP | disclosed |
| US-7834210-B2 | Hair loss prevention by natural amino acid and peptide complexes | BIODERM RESEARCH (US) | 2010-11-16 | — | — | US | disclosed |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | BIODERM RESEARCH (US) | 2009-10-08 | — | — | US | disclosed |
| US-7572933-B2 | Skin and hair restoration by natural amino acid peptide complexes | BIODERM RESEARCH (US) | 2009-08-11 | — | — | US | disclosed |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | BIODERM RESEARCH (US) | 2008-11-20 | — | — | US | disclosed |
| US-7427690-B2 | Multifunction “crown complexes” from amino acids and peptides for skin and hair restoration | BIODERM RESEARCH (US) | 2008-09-23 | — | — | US | disclosed |
| US-20070099886-A1 | Multifunction \"Crown Complexes\" from Amino Acids and Peptides for Skin and Hair Restoration | BIODERM RESEARCH (US) | 2007-05-03 | — | — | US | disclosed |
| EP-0522000-A1 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-01-13 | — | — | EP | disclosed |
| WO-1991014674-A2 | 5-LIPOXYGENASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078195-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | NAMPT, NAPRT, NNT | TYR 1849/4885ALOX5 1786/4885MEN1 1469/4885 |
| US-20200247795-A1 | NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME | NAMPT, NAPRT, NNMT | TYR 2702/4885ALOX5 2652/4885MEN1 2480/4885 |
| US-20080287536-A1 | Skin and Hair Restoration by Natural Amino Acid and Peptide Crown Complexes | MMP17, MC1R, TYR | TYR 3/4885ALOX5 1100/4885MEN1 4115/4885 |
| US-20210171513-A1 | NOVEL COMPOUND FOR INHIBITING NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE AND COMPOSITION CONTAINING SAME | NAMPT, NAPRT, NNMT | TYR 2702/4885ALOX5 2652/4885MEN1 2480/4885 |
| US-20090253668-A1 | Hair Loss Prevention by Natural Amino Acid and Peptide Complexes | MMP1, MMP17, MMP13 | TYR 91/4885ALOX5 1254/4885MEN1 3386/4885 |
| US-20230270692-A1 | COMPOUNDS FOR CHRONIC DISORDERS | FABP6, FABP1, CFTR | TYR 2237/4885ALOX5 236/4885MEN1 3763/4885 |
| US-11795163-B2 | Compound for inhibiting nicotinamide phosphoribosyltransferase and composition containing same | NAMPT, NAPRT, NNT | TYR 1849/4885ALOX5 1786/4885MEN1 1469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.