SCHEMBL3749801

SCHEMBL3749801

CCCCCCCCCCCCCCCCc1cc([NH3+])c(CCCCCCCCCCCCCCCC)c(CCCCCCCCCCCCCCCC)c1CCCCCCCCCCCCCCCC.Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 0.36
TYR P14679 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
CYP19A1 P11511 1/20 0.31
LIPG Q9Y5X9 1/20 0.30
PTGS2 P35354 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904001 0.81 LIPG (0.38) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL23466894 0.80 MEN1 (0.32) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL3752108 0.78 LIPG (0.44) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL29037315 0.74 ALOX5 (0.47) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL250347 0.74 ALOX5 (0.47) ALOX5TYRMEN1TP53CYP3A4
Octane SCHEMBL29076189 0.74 TSHR (0.42) MEN1TSHRKMT2A
SCHEMBL29987424 0.73 TYR (0.35) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL29659437 0.72 ALOX5 (0.46) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL29414438 0.72 ALOX5 (0.46) ALOX5TYRMEN1TP53CYP3A4
SCHEMBL15324096 0.72 CYP19A1 (0.44) ALOX5TYRMEN1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
EP-2041190-B1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2012-10-24 EP disclosed
US-8071835-B2 Process to produce polyolefins using metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-06 US disclosed
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2010-11-18 US disclosed
EP-2041190-A1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2009-04-01 EP disclosed
EP-1920031-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS ExxonMobil Chemical Patents Inc. (US) 2008-05-14 EP disclosed
WO-2008010862-A1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-01-24 WO disclosed
US-20080020928-A1 Process to produce polyolefins using metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2008-01-24 US disclosed
WO-2007011832-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2007011462-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds MUC1, OPRD1, CEL ALOX5 213/4885TYR 1687/4885MEN1 2027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.