SCHEMBL3752108

SCHEMBL3752108

CCCCCCCCCCCCCCc1ccccc1[NH3+].Fc1c(F)c(F)c([B-](c2c(F)c(F)c(F)c(F)c2F)(c2c(F)c(F)c(F)c(F)c2F)c2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 1/20 0.44
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
ALOX5 P09917 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
TYR P14679 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
BID P55957 3/20 0.35
MCL1 Q07820 3/20 0.35
BCL2L1 Q07817 2/20 0.35
BAK1 Q16611 2/20 0.35
KAT8 Q9H7Z6 2/20 0.35
PPARG P37231 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6904001 0.87 LIPG (0.38) LIPGALOX5MEN1TP53CYP3A4
SCHEMBL5670548 0.82 GABRA1 (0.33) MAPTHTT
SCHEMBL129269 0.81 LIPG (0.43) LIPGNR1H2NR1H3ALOX5MEN1
SCHEMBL29362662 0.81 LIPG (0.43) LIPGNR1H2NR1H3ALOX5MEN1
Ammonia Solution, Strong SCHEMBL30387130 0.81 LIPG (0.40) LIPGNR1H2NR1H3ALOX5MEN1
SCHEMBL3749806 0.79 LIPG (0.41) LIPGNR1H2NR1H3ALOX5MEN1
SCHEMBL22589058 0.79 TYR (0.32) LIPGALOX5TYRCYSLTR2CYSLTR1
SCHEMBL3749801 0.78 ALOX5 (0.36) LIPGALOX5MEN1TP53CYP3A4
SCHEMBL31543793 0.77 KCNH2 (0.51) TP53CYP3A4PTGS2
Octane SCHEMBL29076189 0.75 TSHR (0.42) MEN1TSHRKMT2ATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
EP-2041190-B1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS EXXONMOBIL CHEM PATENTS INC (US) 2012-10-24 EP disclosed
US-8071835-B2 Process to produce polyolefins using metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-06 US disclosed
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2010-11-18 US disclosed
EP-2041190-A1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS ExxonMobil Chemical Patents, Inc., A Corporation of the State of Delaware (US) 2009-04-01 EP disclosed
EP-1920031-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS ExxonMobil Chemical Patents Inc. (US) 2008-05-14 EP disclosed
WO-2008010862-A1 PROCESS TO PRODUCE POLYOLEFINS USING METALLOCENE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-01-24 WO disclosed
US-20080020928-A1 Process to produce polyolefins using metallocene catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2008-01-24 US disclosed
WO-2007011832-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed
WO-2007011462-A1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292424-A1 Lubricants from Mixed Alpha-Olefin Feeds MUC1, OPRD1, CEL LIPG 180/4885NR1H2 458/4885NR1H3 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.