Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 7/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL944243 | 0.86 | RAB9A (0.38) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL5047353 | 0.79 | ADORA2B (0.33) | HTTALDH1A1RGS4 | |
| Bromide SCHEMBL4940305 | 0.74 | CYP1A1 (0.48) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL4891645 | 0.70 | PDE1A (0.31) | — | |
| SCHEMBL4900906 | 0.65 | LMNA (0.30) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL942848 | 0.65 | RGS4 (0.36) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL4900911 | 0.64 | LMNA (0.30) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| Iodide SCHEMBL945029 | 0.63 | RAB9A (0.39) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| SCHEMBL4114417 | 0.60 | RAB9A (0.37) | RAB9ALMNAHTTSMN1; SMN2NR2F2 | |
| Iodide SCHEMBL965881 | 0.59 | F12 (0.56) | RAB9AHTTNPC1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8735434-B2 | Compounds as cannabinoid receptor ligands | ABBVIE INC. (US) | 2014-05-27 | — | — | US | disclosed |
| EP-2160393-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | Abbott Laboratories (US) | 2010-03-10 | — | — | EP | disclosed |
| WO-2008144360-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-11-27 | — | — | WO | disclosed |
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 2008-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080287510-A1 | NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS | CNR1, CNR2, GPR18 | RAB9A 1124/4885LMNA 4197/4885HTT 3022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.