SCHEMBL3751912

SCHEMBL3751912

O=C1CC=CN=C1c1ccccn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.43
LMNA P02545 3/20 0.43
CCR1 P32246 2/20 0.43
CCR5 P51681 2/20 0.43
CCR8 P51685 2/20 0.43
P4HTM Q9NXG6 2/20 0.43
CYP1A2 P05177 2/20 0.43
POLB P06746 1/20 0.43
METAP1 P53582 1/20 0.43
BLM P54132 1/20 0.43
HIF1A Q16665 1/20 0.43
DOHH Q9BU89 1/20 0.43
NPC1 O15118 5/20 0.38
RAB9A P51151 5/20 0.38
TP53 P04637 4/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
ALOX15 P16050 2/20 0.38
HTT P42858 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29809937 1.00 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29985874 0.98 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL30362597 0.79 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL4916622 0.79 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL812421 0.79 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL9575339 0.79 KDM4E (0.39) KDM4ELMNACCR1CCR5CCR8
SCHEMBL25222671 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
Hydrochloric Acid SCHEMBL28598655 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28632180 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL29494142 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776958-A Aromatic hydrocarbon carboxylic acid meta-position alkylation product and synthesis method thereof 华南理工大学 2024-03-29 CN claimed
US-9527066-B2 Dihydroxybipyridine complexes of ruthenium and iridium for water oxidation and hydrogenation THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-12-27 US claimed
US-20140219911-A1 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2014-08-07 US claimed
WO-2013033018-A2 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION DREXEL UNIVERSITY (US) 2013-03-07 WO claimed
US-20260082802-A1 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR PRODUCING AN ORGANIC ELECTRONIC COMPONENT PICTIVA DISPLAYS INTERNATIONAL LIMITED (IE) 2026-03-19 US disclosed
CN-117776958-A Aromatic hydrocarbon carboxylic acid meta-position alkylation product and synthesis method thereof 华南理工大学 2024-03-29 CN disclosed
CN-114904492-B Polymer composite microsphere for extracting and purifying diquat metabolite in blood plasma, preparation method, kit and extraction method 浙江哈迈科技有限公司 2023-11-10 CN disclosed
CN-114420633-A Copper deposition in wafer level packaging of integrated circuits 麦克德米德乐思公司 2022-04-29 CN disclosed
CN-110713487-B Novel heterocyclic aromatic hydrazone derivative, pharmaceutically acceptable salt thereof, preparation method and application thereof 南京大学 2022-02-15 CN disclosed
EP-3094325-B1 HETEROARYLS AND USES THEREOF TAKEDA PHARMACEUTICALS CO (JP) 2021-10-13 EP disclosed
CN-111032741-A Stabilization of noble metal catalysts 瓦克化学股份公司 2020-04-17 CN disclosed
CN-110713487-A Novel heterocyclic aromatic hydrazone derivative, pharmaceutically acceptable salt thereof, preparation method and application thereof 南京大学 2020-01-21 CN disclosed
WO-2013033018-A2 DIHYDROXYBIPYRIDINE COMPLEXES OF RUTHENIUM AND IRIDIUM FOR WATER OXIDATION AND HYDROGENATION DREXEL UNIVERSITY (US) 2013-03-07 WO disclosed
US-20100298562-A1 Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2010-11-25 US disclosed
US-20090326186-A1 MESOGEN CONTAINING COMPOUNDS TRANSITIONS OPTICAL, INC. (US) 2009-12-31 US disclosed
EP-2069345-A2 PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES Centre National de la Recherche Scientifique (CNRS) (FR) 2009-06-17 EP disclosed
WO-2008012440-A2 PYRIDAZINE AND PYRROLE COMPOUNDS, PROCESSES FOR OBTAINING THEM AND USES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2008-01-31 WO disclosed
US-6828439-B1 Compounds, composition, and methods for photodynamic therapy ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. 2004-12-07 US disclosed
US-6261538-B1 CHLOROMETHYLATED RESIN WITH AMINE PHOSPHONIUM SALTS CHINA PETROCHEMICAL CORPORATION (CN) 2001-07-17 US disclosed
WO-2000050117-A2 COMPOUNDS, COMPOSITIONS, AND METHODS FOR PHOTODYNAMIC THERAPY ADVANCED RESEARCH AND TECHNOLOGY INSTITUTE, INC. (US) 2000-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260082802-A1 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR PRODUCING AN ORGANIC ELECTRONIC COMPONENT FLNA, FLNB, CDH1 KDM4E 1010/4885LMNA 1892/4885CCR1 4767/4885
US-20100298562-A1 Pyridazine and Pyrrole Compounds, Processes For Obtaining Them and Uses PPOX, PNPO, PLPBP KDM4E 2333/4885LMNA 4332/4885CCR1 3696/4885
US-20090326186-A1 MESOGEN CONTAINING COMPOUNDS MYOC, BMP2, RARG KDM4E 4212/4885LMNA 1261/4885CCR1 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.