Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 6/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7965650 | 0.70 | ADRA2B (0.40) | ADRA2BADRA2CLMNAHTTPOLB | |
| SCHEMBL3752207 | 0.70 | CRBN (0.40) | CRBNDDB1LMNADUTPKM | |
| SCHEMBL176287 | 0.70 | ADRA2C (0.47) | ADRA2BADRA2CLMNAMAPTMAPK1 | |
| SCHEMBL5907658 | 0.70 | CRBN (0.52) | CRBNDDB1DUTPKMHCAR1 | |
| SCHEMBL11034063 | 0.66 | ADRA2B (0.44) | ADRA2BADRA2CLMNANPC1MAPT | |
| SCHEMBL1667781 | 0.66 | MEN1 (0.39) | ADRA2BADRA2CLMNAHTTPOLB | |
| SCHEMBL11667981 | 0.65 | ADRA2C (0.43) | ADRA2BADRA2CLMNAPOLBMAPT | |
| SCHEMBL9795634 | 0.65 | ADRA2C (0.43) | ADRA2BADRA2CLMNAPOLBMAPT | |
| SCHEMBL30729429 | 0.65 | MAPT (0.45) | ADRA2BADRA2CLMNAHTTMAPT | |
| SCHEMBL6046931 | 0.65 | MAPT (0.45) | ADRA2BADRA2CLMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6177437-B1 | VIRICIDES | UNIVERSITY OF MASSACHUSETTS MEDICAL CENTER | 2001-01-23 | — | — | US | disclosed |