Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 6/20 | 0.64 |
| ▸ | CES1 | P23141 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.54 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.54 |
| ▸ | F3 | P13726 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3753532 | 1.00 | HDAC1 (0.67) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL27905641 | 0.98 | CES2 (0.68) | HDAC1CES2CES1MAPTPLIN1 | |
| Benzil SCHEMBL27348338 | 0.93 | CES2 (0.70) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL6311364 | 0.91 | HDAC1 (0.62) | HDAC1CES2CES1MAPTPLIN1 | |
| Potassium Ion SCHEMBL6318653 | 0.87 | HDAC1 (0.58) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL1927729 | 0.86 | HDAC1 (0.67) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL11545296 | 0.86 | HDAC1 (0.67) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL1927732 | 0.86 | HDAC1 (0.67) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL8437189 | 0.86 | HDAC1 (0.67) | HDAC1CES2CES1MAPTPLIN1 | |
| SCHEMBL27792692 | 0.86 | HDAC1 (0.67) | HDAC1MAPTPLIN1LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842830-B2 | Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-11-30 | — | — | US | disclosed |
| US-7842830-B2 | Transition-metal charge-transport materials, methods of fabrication thereof, and methods of use thereof | GEORGIA TECH RESEARCH CORPORATION (US) | 2010-11-30 | — | — | US | disclosed |
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | GEORGIA TECH RESEACH CORPORATION | 2008-05-29 | — | — | US | disclosed |
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | GEORGIA TECH RESEACH CORPORATION | 2008-05-29 | — | — | US | disclosed |
| WO-2005123754-A2 | TRANSITION-METAL CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF | GEORGIA TECH RESEARCH CORPORATION (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080121870-A1 | Transition-Metal Charge Transport Materials, Methods Of Fabrication Thereof, And Methods Of Use Thereof | SLC39A3, SLC6A6, SLC6A9 | HDAC1 3657/4885CES2 1387/4885CES1 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.