Acetonitrile

Acetonitrile

SCHEMBL3755773

CC#N.CO.O.O=CO

nearest known ligand 0.00

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Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Acetonitrile. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetonitrile SCHEMBL28350050 1.00 APLNR (0.32)
Acetonitrile SCHEMBL1832586 1.00
Acetonitrile SCHEMBL7316992 0.96
Acetonitrile SCHEMBL15092908 0.96 APLNR (0.33)
Acetonitrile SCHEMBL16267901 0.96 APLNR (0.33)
Acetonitrile SCHEMBL522737 0.96
Acetonitrile SCHEMBL9936942 0.96 APLNR (0.33)
Acetonitrile SCHEMBL16267560 0.96 APLNR (0.33)
Acetonitrile SCHEMBL28516249 0.96
Acetonitrile SCHEMBL15092655 0.96 APLNR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101623477-A Novel process for Chinese medicinal composition for reducing blood fat and method for preparing novel formulations BEIJING TIANJIAO AOTEQI CHINES 2010-01-13 CN claimed
CN-100522191-C Fingerprint atlas detection method for tanshin polyphenolic acid salts LUGU PHARMACEUTICAL CO LTD (CN) 2009-08-05 CN claimed
CN-1911273-A Fingerprint atlas detection method for powder injection contg. high content of tanshin polyphenolic acid salts LUGU PHARMACEUTICAL CO LTD SHA (CN) 2007-02-14 CN claimed
CN-1264014-C Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2006-07-12 CN claimed
CN-1435688-A Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2003-08-13 CN claimed
CN-117054209-B Dilution of smoke nicotine and extraction and detection method 宁波镇海质谱技术研究院 2024-07-12 CN disclosed
CN-117054209-A Dilution of smoke nicotine and extraction and detection method 宁波镇海质谱技术研究院 2023-11-14 CN disclosed
CN-115364077-B Lonicera edulis lutein preparation, eye drop and application thereof in relieving eye fatigue 陕西美芙康生物科技有限公司 2023-11-10 CN disclosed
CN-114848606-B Salvianolic acid B and powder fog agent capsule and preparation method thereof 惠州市九惠制药股份有限公司 2023-10-31 CN disclosed
CN-116626182-A Azalea quality detection method based on chemical fingerprint spectrum and quality difference components 贵州医科大学 2023-08-22 CN disclosed
CN-116077546-A Lonicera edulis lutein preparation, eye drop and application thereof in relieving eye fatigue 浙江双糖生物科技有限公司 2023-05-09 CN disclosed
CN-115364077-A Lonicera edulis xanthophyll preparation, eye drops and application of eye drops in relieving asthenopia 浙江双糖生物科技有限公司 2022-11-22 CN disclosed
CN-1264014-C Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2006-07-12 CN disclosed
CN-1264014-C Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2006-07-12 CN disclosed
CN-1220489-C Freeze-dried Danhong powder injection for injection and its preparing method QIANLUCHUN SCIENCE AND TECHNOL (CN) 2005-09-28 CN disclosed
CN-1554335-A Freeze-dried Danhong powder injection for injection and its preparing method 北京乾露春科技有限公司 2004-12-15 CN disclosed
CN-1435688-A Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2003-08-13 CN disclosed
CN-1435688-A Method for quantitatively measuring tanshinonic acid B in red sage root XUHUI DISTR CENTRAL HOSPITAL S (CN) 2003-08-13 CN disclosed
US-20010048918-A1 FOOD PRODUCTS CONTAINING BACTERIA WITH CHOLESTEROL LOWERING ACTIVITY THOMAS J. LIPTON, DIVISION OF CONOPCO, INC. 2001-12-06 US disclosed
EP-0792586-A2 Food products containing bacteria with cholesterol lowering activity UNILEVER N.V. (NL) 1997-09-03 EP disclosed