Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | GLS | O94925 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29642483 | 1.00 | ALDH1A1 (0.57) | ALDH1A1KMT2AHPGDHSD17B10GAA | |
| SCHEMBL922425 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KMT2AHPGDHSD17B10POLB | |
| SCHEMBL2623697 | 0.87 | HDAC8 (0.65) | ALDH1A1KMT2AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL5272078 | 0.86 | HDAC8 (0.68) | ALDH1A1KMT2AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL8897691 | 0.86 | HDAC8 (0.68) | ALDH1A1KMT2AHPGDPOLBSMN1; SMN2 | |
| SCHEMBL14594063 | 0.84 | KMT2A (0.60) | ALDH1A1KMT2AHPGDHSD17B10GAA | |
| SCHEMBL27432750 | 0.83 | POLB (0.45) | ALDH1A1KMT2AHPGDHSD17B10GAA | |
| SCHEMBL30098360 | 0.82 | CA12 (0.66) | ALDH1A1KMT2AHPGDHSD17B10GAA | |
| SCHEMBL135305 | 0.82 | CA12 (0.66) | ALDH1A1KMT2AHPGDHSD17B10GAA | |
| SCHEMBL13276318 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1KMT2AHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4182322-B1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARM SPA (IT) | 2024-04-24 | — | — | EP | disclosed |
| US-20240116947-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2024-04-11 | — | — | US | disclosed |
| US-11802181-B2 | Di-amine compound, and heat-resistant resin and resin composition using the same | TORAY INDUSTRIES, INC. (JP) | 2023-10-31 | — | — | US | disclosed |
| CN-114213335-B | Carnosine intermediate and preparation and application of carnosine thereof | 浙江湃肽生物股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-4182322-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2023-05-24 | — | — | EP | disclosed |
| US-RE49481-E1 | Compounds for the treatment and prophylaxis of respiratory syncytial virus disease | HOFFMANN-LA ROCHE INC. (US) | 2023-04-04 | — | — | US | disclosed |
| CN-110698481-B | Heteroaryl pyridone and aza-pyridone amide compounds | 豪夫迈·罗氏有限公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-109906217-B | Diamine compound, heat-resistant resin using same, and resin composition | 东丽株式会社 | 2022-05-10 | — | — | CN | disclosed |
| CN-114213335-A | Carnosine intermediate and preparation and application of carnosine | 浙江湃肽生物有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-114213503-A | Synthesis method of snake venom-like tripeptide | 上海予利生物科技股份有限公司 | 2022-03-22 | — | — | CN | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
| WO-1996013485-A1 | PYRIDOPYRIMIDONES, QUINOLINES AND FUSED N-HERETOCYCLES AS BRADYKININ ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-05-09 | — | — | WO | disclosed |
| WO-1996007642-A1 | PROCESS FOR PRODUCING A β-AMINO ALCOHOL | F. HOFFMANN-LA ROCHE AG (DE) | 1996-03-14 | — | — | WO | disclosed |
| US-4849436-A | TREATMENT OF CARDIOVASCULAR DISORDERS | NELSON RESEARCH & DEVELOPMENT CO. (US) | 1989-07-18 | — | — | US | disclosed |
| EP-0259462-A1 | 1,4-DIHYDROPYRIDINES | Whitby Research Incorporated (US) | 1988-03-16 | — | — | EP | disclosed |
| WO-1987005512-A1 | 1,4-DIHYDROPYRIDINES | NELSON RESEARCH AND DEVELOPMENT COMPANY (US) | 1987-09-24 | — | — | WO | disclosed |
| EP-0197478-A1 | Diphosphonic-acid derivatives, process for preparing them and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1986-10-15 | — | — | EP | disclosed |
| US-4548935-A | Dihydropyridine anti-ischaemic and anti-hypertensive agents, compositions and use | PFIZER INC. (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0150939-A1 | Dihydropyridine anti-ischaemic and antihypertensive agents | Pfizer Limited (GB) | 1985-08-07 | — | — | EP | disclosed |
| US-3994940-A | Preparation of 1-(2-(dimethylamino)ethyl)-6-phenyl-4H-5-triazolo(4,3-a)(1,4)benzodiazepines | THE UPJOHN COMPANY (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116947-A1 | PYRIDO OXAZINE DERIVATIVES AS ALK5 INHIBITORS | TGFBR1, ACVR1, TGFBR2 | ALDH1A1 455/4885KMT2A 3553/4885HPGD 2150/4885 |
| US-11802181-B2 | Di-amine compound, and heat-resistant resin and resin composition using the same | CAD, ARID2, SMC3 | ALDH1A1 2539/4885KMT2A 1021/4885HPGD 3488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.