SCHEMBL3758000

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4662755	0.90	PGR (0.72)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL9234846	0.87	PGR (0.73)	PGRKEAP1ALDH1A1POLB
	SCHEMBL7181531	0.86	PGR (0.72)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL2959233	0.86	PGR (0.72)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL1629146	0.86	PGR (0.74)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL5329582	0.86	PGR (0.71)	PGRGAAALDH1A1LMNARORA
	SCHEMBL20323615	0.85	HTR6 (0.66)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL7183197	0.85	GAA (0.64)	PGRGAAKEAP1NFE2L2ALDH1A1
	SCHEMBL8081768	0.82	KEAP1 (0.79)	PGRGAAKEAP1ALDH1A1POLB
	SCHEMBL31681417	0.82	CYP19A1 (0.68)	PGRALDH1A1LMNAPOLBCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.