Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3764144 | 0.92 | GPR119 (0.47) | GPR119KEAP1NFE2L2SLC2A1TP53 | |
| SCHEMBL3758467 | 0.83 | GPR119 (0.45) | GPR119KEAP1NFE2L2SLC2A1TP53 | |
| SCHEMBL3754821 | 0.77 | CCR5 (0.44) | — | |
| SCHEMBL3758463 | 0.76 | KEAP1 (0.46) | GPR119KEAP1NFE2L2 | |
| SCHEMBL3757151 | 0.76 | GPR119 (0.50) | GPR119TP53LMNA | |
| SCHEMBL3764139 | 0.74 | ALDH1A1 (0.43) | GPR119KEAP1NFE2L2 | |
| SCHEMBL4236458 | 0.74 | GPR119 (0.51) | GPR119TP53LMNA | |
| SCHEMBL4243344 | 0.72 | GPR119 (0.48) | GPR119TP53LMNA | |
| SCHEMBL3764336 | 0.71 | CCR5 (0.46) | — | |
| SCHEMBL5649714 | 0.70 | GPR119 (0.61) | GPR119SLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2010-11-25 | — | — | US | disclosed |
| US-7790747-B2 | Chemokine receptor binding compounds | GENZYME CORPORATION (US) | 2010-09-07 | — | — | US | disclosed |
| US-20090099205-A1 | Chemokine receptor binding compounds | GENZYME CORPORATION | 2009-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298366-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | CCR5, CXCR3, CCL5 | GPR119 207/4885KEAP1 2625/4885NFE2L2 3160/4885 |
| US-20090099205-A1 | Chemokine receptor binding compounds | CCR5, CXCR3, CCL5 | GPR119 207/4885KEAP1 2625/4885NFE2L2 3160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.