SCHEMBL376145

SCHEMBL376145

O=COc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.45
RAB9A P51151 3/20 0.43
NPC1 O15118 2/20 0.43
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
BCHE P06276 1/20 0.40
CES1 P23141 1/20 0.40
MAOA P21397 2/20 0.38
KDM4E B2RXH2 3/20 0.37
ALDH1A1 P00352 2/20 0.37
MAPT P10636 2/20 0.37
GAA P10253 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPK1 P28482 1/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628931 0.84 KDM4E (0.41) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL14803713 0.83 PNMT (0.45) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL6902826 0.82 DRD2 (0.41) BCHECES1MAOA
SCHEMBL28832018 0.80 PNMT (0.52) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL27471730 0.79 MAOA (0.42) RAB9ANPC1HTR2BBCHECES1
SCHEMBL895389 0.79 CTSS (0.46) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL31143104 0.78 LMNA (0.47) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL15141606 0.77 PNMT (0.49) PNMTRAB9ANPC1HTR7HTR2B
SCHEMBL8854649 0.77 DRD2 (0.54) PNMTRAB9ANPC1KDM4EALDH1A1
SCHEMBL29090327 0.77 PNMT (0.49) PNMTRAB9ANPC1HTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 616 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4396163-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2024-07-10 EP claimed
EP-4396173-A1 HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM BASF SE (DE) 2024-07-10 EP claimed
CN-117881667-A Herbicide malonamides containing a condensed ring system 巴斯夫欧洲公司 2024-04-12 CN claimed
CN-117881662-A Herbicide malonamide containing monocyclic heteroaromatic ring 巴斯夫欧洲公司 2024-04-12 CN claimed
WO-2023207710-A1 ANTIBODY-DRUG CONJUGATE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 四川科伦博泰生物医药股份有限公司 2023-11-02 WO claimed
CN-114656391-B Polyhydroxy pyrrolidine compound and preparation method and application thereof 中国科学院化学研究所 2023-10-24 CN claimed
CN-116731124-A Process for the preparation of cyclosporin and intermediates thereof 齐鲁制药有限公司 2023-09-12 CN claimed
WO-2023031199-A1 HERBICIDAL MALONAMIDES CONTAINING MONOCYCLIC HETEROAROMATIC RINGS BASF SE (DE) 2023-03-09 WO claimed
WO-2023031200-A1 HERBICIDAL MALONAMIDES CONTAINING A CONDENSED RING SYSTEM BASF SE (DE) 2023-03-09 WO claimed
CN-115746222-A Composite water reducing agent and preparation process thereof 广东六合新型建材有限公司 2023-03-07 CN claimed
US-5674807-A ARYLOXYPICOLINAMIDES SYNERGISTICALLY ENHANCED BY COMBINATION WITH ONE OR MORE SELECTED HERBICIDES AMERICAN CYANAMID COMPANY (US) 1997-10-07 US claimed
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0785197-A2 2-oxo and 2-thio-1,2-dihydroquinolinyl-oxazolidinones BAYER AG (DE) 1997-07-23 EP claimed
EP-0665715-B1 HERBICIDE MIXTURES SHELL INT RESEARCH (NL) 1997-01-08 EP claimed
US-5449778-A Peptide intermediates WARNER-LAMBERT COMPANY (US) 1995-09-12 US claimed
EP-0665715-A1 HERBICIDE MIXTURES. SHELL INT RESEARCH (NL) 1995-08-09 EP claimed
EP-0637305-A1 NOVEL CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1995-02-08 EP claimed
WO-1994007368-A1 HERBICIDE MIXTURES SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 1994-04-14 WO claimed
US-5264577-A Cyclic amino acids and derivatives thereof WARNER-LAMBERT COMPANY (US) 1993-11-23 US claimed
WO-1993021176-A1 NOVEL CYCLIC AMINO ACIDS AND DERIVATIVES THEREOF WARNER-LAMBERT COMPANY (US) 1993-10-28 WO claimed