Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | DRD5 | P21918 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CD69 | Q07108 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899118 | 0.83 | ADRA2A (0.33) | — | |
| SCHEMBL376145 | 0.82 | PNMT (0.45) | MAOABCHECES1 | |
| SCHEMBL1581695 | 0.78 | MAOA (0.48) | DRD2DRD1DRD5DRD3MAOA | |
| SCHEMBL28120988 | 0.78 | ALDH1A1 (0.46) | DRD2DRD1DRD5DRD3 | |
| SCHEMBL27471730 | 0.75 | MAOA (0.42) | DRD2DRD3MAOADRD4BCHE | |
| SCHEMBL11575327 | 0.75 | DRD1 (0.45) | DRD2DRD1DRD5DRD3CYP1A2 | |
| SCHEMBL28263467 | 0.75 | DRD2 (0.67) | DRD2DRD1DRD5DRD3HTR2A | |
| SCHEMBL2399109 | 0.74 | RXRA (0.46) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7631718 | 0.73 | DRD2 (0.33) | DRD2DRD1DRD5DRD3CYP1A2 | |
| SCHEMBL9881101 | 0.72 | ALDH1A1 (0.42) | DRD2DRD1DRD5DRD3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |