SCHEMBL376878

SCHEMBL376878

CCc1cnc(OC(=O)O)c(OC(=O)O)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.37
PARP1 P09874 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
PTGS2 P35354 2/20 0.35
GABRP O00591 2/20 0.33
GABRD O14764 2/20 0.33
GABRA1 P14867 2/20 0.33
GABRB1 P18505 2/20 0.33
GABRG2 P18507 2/20 0.33
GABRB3 P28472 2/20 0.33
GABRA5 P31644 2/20 0.33
GABRA3 P34903 2/20 0.33
GABRA2 P47869 2/20 0.33
GABRB2 P47870 2/20 0.33
GABRA4 P48169 2/20 0.33
GABRE P78334 2/20 0.33
GABRA6 Q16445 2/20 0.33
GABRG1 Q8N1C3 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9839366 0.87 SMN1; SMN2 (0.38) PKMNPC1RAB9ASMN1; SMN2TP53
SCHEMBL8649523 0.84 HCAR2 (0.34) NPC1RAB9ATP53ALDH1A1LMNA
SCHEMBL9678306 0.80 CUL4A (0.39) PKMPARP1PTGS2GABRPGABRD
SCHEMBL3837299 0.77 SLC13A5 (0.37) PARP1RAB9ASMN1; SMN2PTGS2CYP2C9
SCHEMBL8566221 0.74 AGBL2 (0.38) PKMKDM4E
SCHEMBL9838667 0.73 BCHE (0.33) LMNAMAPT
SCHEMBL8785759 0.72 KDM4E (0.43) SMN1; SMN2TP53ALDH1A1KMT2ALMNA
SCHEMBL28484662 0.72 HPGD (0.42) RAB9ASMN1; SMN2KMT2ALMNAKDM4E
SCHEMBL7720520 0.71 NNMT (0.42) SMN1; SMN2GABRPGABRDGABRA1GABRB1
SCHEMBL7808610 0.71 ALOX15 (0.44) NPC1RAB9ASMN1; SMN2TP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2739169-B1 POROUS CATALYTIC MATRICES FOR ELIMINATION OF TOXICANTS FOUND IN TOBACCO COMBUSTION PRODUCTS MASSACHUSETTS INST TECHNOLOGY (US) 2019-06-12 EP claimed
EP-3284847-B1 CORROSION INHIBITOR COMPOSITION FOR MAGNESIUM OR MAGNESIUM ALLOYS HELMHOLTZ ZENTRUM GEESTHACHT (DE) 2019-01-02 EP claimed
EP-1644333-B1 IN-SITU TREATMENT OF PYRIDINE-2,3-DICARBOXYLIC ACID ESTERS WITH AN OXIDIZING AGENT BASF SE (DE) 2009-09-23 EP claimed
EP-0503332-B1 Process for extracting pyridine and quinoline dicarboxylic acids from aqueous media AMERICAN CYANAMID CO (US) 1998-08-26 EP claimed
EP-0594993-B1 Method for the preparation of 2,3-pyridine-dicarboxylic acids and derivatives thereof AMERICAN CYANAMID CO (US) 1997-05-28 EP claimed
EP-0491140-B1 Method for the preparation of substituted and unsbustituted 2,3-pyridine and quinolinedicarboxylic acids AMERICAN CYANAMID CO (US) 1997-04-02 EP claimed
EP-0584470-B1 Process for the preparation of 2,3-pyridinedicarboxylic acids from 3-(2-imidazolin-2-yl)picolinic acids AMERICAN CYANAMID CO (US) 1995-08-16 EP claimed
EP-0331899-B1 A method for the sequential oxidation of substituted-8-hydroxy-quinolines to produce substituted-pyridine-2,3-dicarboxylic acids AMERICAN CYANAMID CO (US) 1994-04-27 EP claimed
EP-0259687-B1 METHOD FOR THE PREPARATION OF PYRIDINE-2,3-DICARBOXYLIC ACIDS AMERICAN CYANAMID COMPANY (US) 1991-07-03 EP claimed
EP-1687462-B1 METHOD FOR ELECTROCHEMICAL PRODUCTION OF A CRYSTALLINE POROUS METAL ORGANIC SKELETON MATERIAL FRAUNHOFER GES FORSCHUNG (DE) 2019-03-13 EP disclosed
EP-2798013-B1 ANTI-REFLECTIVE COATING LEIBNIZ INST FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2016-08-17 EP disclosed
EP-2230288-B1 METAL-ORGANIC FRAMEWORKS IN REFRIGERATION/HEATING MACHINES BASF SE (DE) 2016-05-25 EP disclosed
EP-2408536-B1 PROCESS FOR SEPARATING ACID GASES USING AMINE IMPREGNATED METAL ORGANIC FRAMEWORKS BASF SE (DE) 2014-07-30 EP disclosed
EP-2117676-B1 METHOD FOR SEPARATING GASES USING A POROUS METAL ORGANIC FRAMEWORK MATERIAL BASF SE (DE) 2014-06-25 EP disclosed
EP-1785428-A1 Doped metal organic framework materials BASF AKTIENGESELLSCHAFT (DE) 2007-05-16 EP disclosed
WO-2007023134-A1 METHOD FOR PRODUCING ORGANOMETALLIC FRAMEWORK MATERIALS CONTAINING MAIN GROUP METAL IONS BASF AKTIENGESELLSCHAFT (DE) 2007-03-01 WO disclosed
WO-2006125739-A1 SUSPENSION FOR REDUCING ODOURS BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
EP-1674555-A1 Concentration of methane in methane containing gas mixtures by adsorption BASF AKTIENGESELLSCHAFT (DE) 2006-06-28 EP disclosed
EP-0470445-A1 Process for the preparation of 5-alkylpyridin-2,3-dicarboxylates HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-12 EP disclosed
EP-0233150-A2 Process for the preparation of 2-(Imidazolin-2-yl)-pyridine and like quinoline-3-carboxylic acids CIBA-GEIGY AG (CH) 1987-08-19 EP disclosed