SCHEMBL8566221

SCHEMBL8566221

O=C(O)Oc1cc(F)cnc1OC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AGBL2 Q5U5Z8 1/20 0.38
HCAR2 Q8TDS4 1/20 0.36
PTGER4 P35408 4/20 0.33
SSTR4 P31391 1/20 0.32
KDM4E B2RXH2 1/20 0.31
ASPH Q12797 1/20 0.31
KDM8 Q8N371 1/20 0.31
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL167767 0.83 AGBL2 (0.39) AGBL2HCAR2PTGER4SSTR4KDM4E
SCHEMBL3837299 0.78 SLC13A5 (0.37) HCAR2PTGER4KDM4E
SCHEMBL7720520 0.75 NNMT (0.42)
SCHEMBL9838667 0.74 BCHE (0.33) HCAR2
SCHEMBL376878 0.74 PKM (0.37) KDM4EPKM
SCHEMBL16554531 0.74 SQOR (0.38) AGBL2
SCHEMBL9839366 0.71 SMN1; SMN2 (0.38) KDM4EPKM
SCHEMBL8649523 0.71 HCAR2 (0.34) HCAR2
SCHEMBL4872865 0.71 ALOX15 (0.30)
SCHEMBL21408256 0.69 PDGFRB (0.39) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0661282-B1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AG (DE) 1998-04-22 EP disclosed
EP-0661282-A1 Pyridine-2,3-dicarboxylic imides, process for their preparation and their use to control the growth of unwanted plants BASF AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed