Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837299 | 0.75 | SLC13A5 (0.37) | NNMTSMN1; SMN2TSHR | |
| SCHEMBL8566221 | 0.75 | AGBL2 (0.38) | — | |
| SCHEMBL8785740 | 0.75 | PTGS2 (0.50) | TSHRMAPK1LMNA | |
| SCHEMBL30418806 | 0.74 | NNMT (0.50) | NNMTSMN1; SMN2HPGDSTSHRMKNK1 | |
| SCHEMBL8787364 | 0.72 | MAPT (0.46) | SMN1; SMN2PSMD14MAPK1LMNA | |
| SCHEMBL376878 | 0.71 | PKM (0.37) | SMN1; SMN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL9838667 | 0.71 | BCHE (0.33) | LMNA | |
| SCHEMBL8746464 | 0.71 | GABRP (0.31) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL27259754 | 0.69 | KDM4E (0.54) | SMN1; SMN2TSHRGABRPGABRDGABRA1 | |
| SCHEMBL9839366 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728744-B1 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA AG (CH) | 2002-04-10 | — | — | EP | disclosed |
| EP-0627422-B1 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles | LONZA AG (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0728744-A2 | Process for the preparation of carboxylic acids of nitrogen-containing heterocycles | LONZA A.G. (CH) | 1996-08-28 | — | — | EP | disclosed |
| EP-0627422-A2 | Process for the preparation of carboxamides of nitrogen-containing aromatic heterocycles, as well as their use | LONZA A.G. (CH) | 1994-12-07 | — | — | EP | disclosed |