SCHEMBL3770445

SCHEMBL3770445

O=C(O)c1cc2c(cc1C(=O)O)C(c1ccc(F)c(F)c1F)(c1ccc(F)c(F)c1F)c1cc(C(=O)O)c(C(=O)O)cc1O2

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
MAP2K1 Q02750 2/20 0.35
MAP2K2 P36507 1/20 0.35
HCAR3 P49019 2/20 0.33
HCAR2 Q8TDS4 2/20 0.33
RARA P10276 1/20 0.31
RARB P10826 1/20 0.31
RARG P13631 1/20 0.31
RXRA P19793 1/20 0.31
ALOX5 P09917 1/20 0.31
ALB P02768 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3775432 0.91 CNR1 (0.34) CES2CES1MAP2K1MAP2K2HCAR3
SCHEMBL3274334 0.73 ALOX5 (0.41) ALOX5
SCHEMBL3272491 0.69 ALOX5 (0.34) RARARARBRARGRXRAALOX5
SCHEMBL29405016 0.68 ASPH (0.34) RXRAALOX5
SCHEMBL715286 0.68 ASPH (0.34) RXRAALOX5
SCHEMBL29617167 0.68 ASPH (0.34) RXRAALOX5
SCHEMBL29271883 0.67 SMN1; SMN2 (0.42) ALOX5
SCHEMBL9455649 0.66 KMT2A (0.34) RXRAALOX5
SCHEMBL3471311 0.66 NOTUM (0.33) RARARARBRARGRXRAALOX5
SCHEMBL241797 0.65 CES2 (0.70) CES2CES1MAP2K1MAP2K2ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7851121-B2 Photosensitive polyimide composition and polyimide precursor composition CENTRAL GLASS CO., LTD. (JP) 2010-12-14 US disclosed
US-20090176172-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION AND POLYIMIDE PRECURSOR COMPOSITION CENTRAL GLASS CO., LTD. (JP) 2009-07-09 US disclosed
WO-2007092011-A1 PHOTOSENSITIVE POLYIMIDE COMPOSITION AND POLYIMIDE PRECURSOR COMPOSITION CENTRAL GLASS CO., LTD. (JP) 2007-08-16 WO disclosed