Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.49 |
| ▸ | PAOX | Q6QHF9 | 6/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26748552 | 0.88 | PAOX (0.47) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL459515 | 0.86 | EPHX2 (0.40) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL28801749 | 0.86 | EPHX2 (0.43) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL373838 | 0.84 | EPHX2 (0.39) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL20998615 | 0.83 | PAOX (0.50) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL13902111 | 0.81 | KDM4E (0.71) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| Thiourea SCHEMBL14990305 | 0.80 | PAOX (0.38) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL14990106 | 0.79 | PAOX (0.43) | EPHX2PAOXADRA1AKDM4EMAPK1 | |
| SCHEMBL24572062 | 0.79 | KDM4E (0.76) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL6427110 | 0.79 | ADRA1A (0.54) | PAOXADRA1AKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214188-A1 | COMPOSITIONS FOR STABILIZING AN ISOTHIOCYANATE | VIO CHEMICALS AG (CH) | 2021-10-28 | — | — | WO | disclosed |
| US-20130142739-A1 | PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME | AURIGA INTERNATIONAL (BE) | 2013-06-06 | — | — | US | disclosed |
| US-20130142739-A1 | PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME | AURIGA INTERNATIONAL (BE) | 2013-06-06 | — | — | US | disclosed |
| US-20130142739-A1 | PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME | AURIGA INTERNATIONAL (BE) | 2013-06-06 | — | — | US | disclosed |
| WO-2012010644-A1 | PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME | AURIGA INTERNATIONAL (BE) | 2012-01-26 | — | — | WO | disclosed |
| EP-2409693-A2 | Isothiocyanates and derivatives for use in the treatment and / or prevention of polymorphous light eruptions | Auriga International (BE) | 2012-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142739-A1 | PROCESS FOR THE SYNTHESIS OF ISOTHIOCYANATES AND DERIVATIVES THEREOF AND USES OF SAME | TST, CBS, SRM | EPHX2 2218/4885PAOX 3642/4885ADRA1A 3447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.