Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 3/20 | 0.62 |
| ▸ | HTR2B | P41595 | 1/20 | 0.62 |
| ▸ | RHOC | P08134 | 1/20 | 0.62 |
| ▸ | RHOA | P61586 | 1/20 | 0.62 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244008 | 0.84 | TAS1R3 (0.70) | HTR2BEPHX2LMNARAB9ANPC1 | |
| SCHEMBL3771553 | 0.82 | KCNK3 (0.63) | HTR2BEPHX2PTGS1KCNK3 | |
| SCHEMBL1534374 | 0.81 | RHOC (0.71) | RHOCRHOAP2RX1PTGS1MAPT | |
| SCHEMBL13973019 | 0.80 | HTR2B (0.62) | HTR2BKCNK3LMNAANO1RAB9A | |
| SCHEMBL24166611 | 0.79 | NPC1 (0.62) | HTR2BEPHX2LMNAANO1RAB9A | |
| SCHEMBL2472548 | 0.78 | MEN1 (0.70) | P2RX1PTGS1MAPTKCNK3LMNA | |
| SCHEMBL3777230 | 0.78 | ALDH1A1 (0.63) | HTR2BRAB9ANPC1PKMALOX15 | |
| SCHEMBL15460609 | 0.78 | MAPT (0.60) | ACKR3EPHX2P2RX1PTGS1MAPT | |
| SCHEMBL3764424 | 0.78 | HTR2B (0.63) | ACKR3HTR2BMAPTLMNAANO1 | |
| SCHEMBL15530059 | 0.78 | RXFP1 (0.71) | ACKR3EPHX2P2RX1PTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | NOVASAID AB (SE) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324086-A1 | COMPOUNDS AND METHODS | IL1B, LITAF, CYP11B1 | ACKR3 1463/4885HTR2B 2255/4885RHOC 4277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.