SCHEMBL3777140

SCHEMBL3777140

C=COC(C)Oc1ccc([S+](c2ccc(C(C)(C)C)cc2)c2ccc(C(C)(C)C)cc2)cc1.O=S(=O)([O-])c1ccccc1C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 5/20 0.35
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SLC22A12 Q96S37 4/20 0.33
GAA P10253 1/20 0.32
KMT2A Q03164 1/20 0.32
FFAR1 O14842 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3776616 0.93 SLC22A12 (0.34) HSD11B1SLC22A12GAAKMT2ARAB9A
SCHEMBL5445938 0.82 HSD11B1 (0.47) HSD11B1SLC22A12KMT2AFFAR1FFAR4
SCHEMBL3777143 0.81 SMN1; SMN2 (0.37) HSD11B1LMNAHTTSMN1; SMN2GAA
SCHEMBL452162 0.80 HSD11B1 (0.45) HSD11B1SLC22A12KMT2AFFAR1FFAR4
SCHEMBL29754085 0.80 HSD11B1 (0.45) HSD11B1SLC22A12KMT2AFFAR1FFAR4
Trifluoromethanesulfonic Acid SCHEMBL2572040 0.79 GPR3 (0.31)
Trifluoromethanesulfonic Acid SCHEMBL2570839 0.79 ACHE (0.31)
SCHEMBL3778770 0.77 FABP3 (0.32)
SCHEMBL3789167 0.77 HSD11B1 (0.45) HSD11B1LMNASLC22A12KMT2AFFAR1
SCHEMBL450233 0.75 GAA (0.53) HSD11B1LMNASMN1; SMN2SLC22A12GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7858287-B2 Photosensitive resin, and photosensitive composition HYOGO PREFECTURE (JP) 2010-12-28 US disclosed
US-20090142697-A1 PHOTOSENSITIVE RESIN, AND PHOTOSENSITIVE COMPOSITION TOYO GOSEI CO., LTD. (JP) 2009-06-04 US disclosed