SCHEMBL3780732

SCHEMBL3780732

NC1CC(=O)N(OC(=O)CCCC(=O)O)C1=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
SLC22A6 Q4U2R8 1/20 0.32
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6767254 0.84 TSHR (0.37) TSHRSLC22A6
SCHEMBL22064125 0.82 ALDH1A1 (0.32) ALDH1A1TP53MAPTHPGDHTT
SCHEMBL4969197 0.81 TSHR (0.33) TSHR
SCHEMBL208988 0.79 TSHR (0.36) TSHRALDH1A1
SCHEMBL23111823 0.79 TSHR (0.35) TSHR
SCHEMBL7905682 0.79 TSHR (0.37) TSHR
SCHEMBL30806937 0.79 TSHR (0.33) TSHR
SCHEMBL4858440 0.76 LMNA (0.31)
SCHEMBL34382 0.76 TSHR (0.44) TSHRSLC22A6
SCHEMBL9443639 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10688216-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2020-06-23 US claimed
US-9878066-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2018-01-30 US claimed
US-20170049924-A1 CROSSLINKED GELS COMPRISING POLYALKYLENEIMINES, AND THEIR USES AS MEDICAL DEVICES HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2017-02-23 US claimed
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2023-11-28 US disclosed
US-20210275718-A1 Crosslinked Gels Comprising Polyalkyleneimines, And Their Uses As Medical Devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2021-09-09 US disclosed
US-11027043-B1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2021-06-08 US disclosed
US-10688216-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2020-06-23 US disclosed
US-20190001018-A1 CROSSLINKED GELS COMPRISING POLYALKYLENEIMINES, AND THEIR USES AS MEDICAL DEVICES HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2019-01-03 US disclosed
US-9878066-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2018-01-30 US disclosed
US-20170049924-A1 CROSSLINKED GELS COMPRISING POLYALKYLENEIMINES, AND THEIR USES AS MEDICAL DEVICES HYPERBRANCH MEDICAL TECHNOLOGY, INC. 2017-02-23 US disclosed
US-9393344-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2016-07-19 US disclosed
EP-1996243-B1 CROSSLINKED GELS COMPRISING POLYALKYLENEIMINES, AND THEIR USES AS MEDICAL DEVICES HYPERBRANCH MEDICAL TECHNOLOGY INC (US) 2014-04-23 EP disclosed
EP-2178997-A2 POLYMERIC MASKING MATERIALS FOR SPANNING WOUND SITES, AND METHODS OF USE THEREOF Hyperbranch Medical Technology, Inc. (US) 2010-04-28 EP disclosed
US-20100069927-A1 Polymeric Masking Materials for Spanning Wound Sites, and Methods of Use Thereof HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2010-03-18 US disclosed
WO-2009015124-A2 POLYMERIC MASKING MATERIALS FOR SPANNING WOUND SITES, AND METHODS OF USE THEREOF HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2009-01-29 WO disclosed
US-20070196454-A1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices HYPERBRANCH MEDICAL TECHNOLOGY, INC. (US) 2007-08-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10688216-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, LIG3, PLOD2 TSHR 4855/4885SLC22A6 4395/4885ALDH1A1 842/4885
US-20210275718-A1 Crosslinked Gels Comprising Polyalkyleneimines, And Their Uses As Medical Devices PLOD3, LIG3, PLOD2 TSHR 4855/4885SLC22A6 4395/4885ALDH1A1 842/4885
US-11826485-B2 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, LIG3, PLOD2 TSHR 4855/4885SLC22A6 4395/4885ALDH1A1 842/4885
US-20070196454-A1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, PLOD2, PLOD1 TSHR 4792/4885SLC22A6 4232/4885ALDH1A1 950/4885
US-11027043-B1 Crosslinked gels comprising polyalkyleneimines, and their uses as medical devices PLOD3, PLOD2, PLOD1 TSHR 4811/4885SLC22A6 4283/4885ALDH1A1 889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.