Chloroform

Chloroform

SCHEMBL378302

CCN(CC)CC.ClC(Cl)Cl

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL7930106 0.96 LMNA (0.31) LMNA
Chloroform SCHEMBL83188 0.93 CYP2C9 (0.32)
Chloroform SCHEMBL537028 0.89 ALDH1A1 (0.40)
Chloroform SCHEMBL2007196 0.89 CYP1A2 (0.31)
Benzene SCHEMBL11096471 0.89 SIGMAR1 (0.38) LMNA
Cyclohexane SCHEMBL10673286 0.89 HRH3 (0.31)
SCHEMBL27936530 0.88 ALDH1A1 (0.46)
Chloroform SCHEMBL8348906 0.87 ALDH1A1 (0.38)
Hexane SCHEMBL620765 0.87 PLA2G1B (0.44) LMNA
Cyclohexane SCHEMBL11847430 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113433257-B Method for separating and measuring carnitine enantiomer in health food 杭州海关技术中心 2022-09-16 CN claimed
CN-113219097-B Method for splitting and measuring carnitine enantiomer in infant formula milk powder 杭州海关技术中心 2022-06-24 CN claimed
CN-113433257-A Method for separating and determining carnitine enantiomer in health food based on ultra-high performance synthetic phase chromatography technology 杭州海关技术中心 2021-09-24 CN claimed
CN-113219097-A Method for splitting and determining carnitine enantiomer in infant formula milk powder based on ultra-high performance synthetic phase chromatography 杭州海关技术中心 2021-08-06 CN claimed
CN-112684089-A Method for separating and determining carnitine enantiomer in health food based on ultra-high performance synthetic phase chromatography technology 杭州海关技术中心 2021-04-20 CN claimed
CN-102504250-B Ammonia ester bond small molecular weight polyethyleneimine (PEI) cross-linked derivatives, and preparation method, application and composition thereof UNIV SHANGHAI JIAOTONG 2013-09-25 CN claimed
CN-102432877-B Amido bond small-molecular-weight polyethyleneimine (PEI) crosslinked derivative, and preparation method, application and composite thereof UNIV SHANGHAI JIAOTONG 2013-08-07 CN claimed
CN-103149317-A Method for promptly detecting biogenic amine in food UNIV JIANGNAN 2013-06-12 CN claimed
CN-102504250-A Ammonia ester bond small molecular weight polyethyleneimine (PEI) cross-linked derivatives, and preparation method, application and composition thereof UNIV SHANGHAI JIAOTONG 2012-06-20 CN claimed
CN-102432877-A Amido bond crosslinking small molecular weight PEI derivative, preparation method, application and compound UNIV SHANGHAI JIAOTONG 2012-05-02 CN claimed
US-20240238260-A1 NORADRENERGIC AND SPECIFIC SEROTONERGIC ANXIOLYTIC AND ANTIDEPRESSANT, METHOD FOR THE PRODUCTION AND USE THEREOF SAVCHUK, NIKOLAY FILIPPOVICH 2024-07-18 US disclosed
CN-116879418-A T-test method for distinguishing difference degree of nicotine oil-water distribution coefficient measured by different instruments 云南中烟工业有限责任公司 2023-10-13 CN disclosed
CN-116818934-A Non-parameter test for determining influence degree of discriminating instrument on nicotine oil-water distribution coefficient 云南中烟工业有限责任公司 2023-09-29 CN disclosed
CN-116593616-A Method for judging degree of difference of apparent oil-water distribution coefficients of nicotine measured by different instruments 云南中烟工业有限责任公司 2023-08-15 CN disclosed
CN-116459223-A Preparation method of levocarnitine powder injection 哈尔滨松鹤制药有限公司 2023-07-21 CN disclosed
US-4111924-A REACTION WITH MERCURIC ACETATE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-09-05 US disclosed
US-4100346-A Certain 7(o-amino-methyl- or methylaminomethylphenyl- or cyclohexadienyl- or thienylacetamide)-3[1-carboxymethyl-(or ethyl- or propyl-)-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids BRISTOL-MYERS COMPANY (US) 1978-07-11 US disclosed
US-4096146-A ANTIMALARIA, ANTIARRHYTHMIA HOFFMANN-LA ROCHE INC. (US) 1978-06-20 US disclosed
US-3931192-A Process for piperidine intermediates for quinine, quinidine and analogs thereof HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed
US-3931193-A ANTIMALARIA, ANTIARRHYTHMIA INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238260-A1 NORADRENERGIC AND SPECIFIC SEROTONERGIC ANXIOLYTIC AND ANTIDEPRESSANT, METHOD FOR THE PRODUCTION AND USE THEREOF HTR2A, HTR1A, HTR2B LMNA 224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.