Chloroform

Chloroform

SCHEMBL83188

CCN(CC)CC.CO.ClC(Cl)Cl

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 2/20 0.32
HPGD P15428 2/20 0.32
MAPK1 P28482 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CYP1A2 P05177 1/20 0.32
HIF1A Q16665 1/20 0.32
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
THRB P10828 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
RECQL P46063 1/20 0.31
CACNA1B Q00975 1/20 0.31
APBA1 Q02410 1/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
HKDC1 Q2TB90 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL2007196 0.97 CYP1A2 (0.31) CYP2C9HPGDMAPK1HSD17B10CYP1A2
Chloroform SCHEMBL378302 0.93 LMNA (0.33)
Cyclohexane SCHEMBL11847430 0.91
Chloroform SCHEMBL537028 0.90 ALDH1A1 (0.40) CYP2C9HPGDMAPK1HSD17B10CYP1A2
Chloroform SCHEMBL7930106 0.89 LMNA (0.31)
Isopropyl Alcohol SCHEMBL6666765 0.88 ALDH1A1 (0.33) ALDH1A1
Hexane SCHEMBL27647104 0.88 PLA2G1B (0.41) HSD17B10ALDH1A1MEN1THRBKMT2A
Chloroform SCHEMBL8348906 0.87 ALDH1A1 (0.38) CYP2C9HPGDMAPK1HSD17B10CYP1A2
Chloromethane SCHEMBL375766 0.85 CYP2C9 (0.35) CYP2C9HPGDMAPK1HSD17B10CYP1A2
Methyl Alcohol SCHEMBL341831 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 380 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101554417-B Quality control method of antitumor Chinese medicine composition NANJING ZHONGKE GROUP CO LTD 2011-09-21 CN claimed
CN-101554417-A Quality control method of antitumor Chinese medicine composition NANJING ZHONGKE GROUP CO LTD (CN) 2009-10-14 CN claimed
EP-4349846-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) 2024-04-10 EP disclosed
CN-117412983-A Chimeric nucleic acid oligomer comprising phosphorothioate and borazine phosphate, and method for producing same 学校法人东京理科大学 2024-01-16 CN disclosed
US-11845724-B2 USP30 inhibitors and uses thereof VINCERE BIOSCIENCES, INC. (US) 2023-12-19 US disclosed
WO-2023191088-A1 PLANT-DERIVED ORGANOCATALYST 協和ファーマケミカル株式会社 2023-10-05 WO disclosed
WO-2023105494-A1 CATIONIC STEROID COMPOUNDS, METHOD OF OBTAINING THEREOF, FORMULATIONS COMPRISING THEREOF AND THEIR USES UNIVERSIDADE DO PORTO (PT) 2023-06-15 WO disclosed
WO-2023085392-A1 ANTI-SARS-COV-2 DRUG 国立大学法人鹿児島大学 2023-05-19 WO disclosed
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid SHIONOGI & CO., LTD. (JP) 2023-05-02 US disclosed
WO-2022255469-A1 CHIMERIC NUCLEIC ACID OLIGOMER INCLUDING PHOSPHOROTHIOATE AND BORANOPHOSPHATE, AND METHOD FOR PRODUCING SAME 学校法人東京理科大学 2022-12-08 WO disclosed
US-20220315531-A1 USP30 INHIBITORS AND USES THEREOF VINCERE BIOSCIENCES, INC. 2022-10-06 US disclosed
US-4096146-A ANTIMALARIA, ANTIARRHYTHMIA HOFFMANN-LA ROCHE INC. (US) 1978-06-20 US disclosed
US-4093610-A CYCLIC DODECAPEPTIDE, MULTISTAGE AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed
US-4091115-A ANTIDEPRESSANTS ROUSSEL UCLAF (FR) 1978-05-23 US disclosed
US-4064339-A Antibiotic aminoglycosides, processes of preparation and pharmaceutical compositions ROUSSEL UCLAF (FR) 1977-12-20 US disclosed
US-4009273-A CNS STIMULANTS ROUSSEL-UCLAF (FR) 1977-02-22 US disclosed
US-3953453-A ANTIMALARIAL AGENTS HOFFMANN-LA ROCHE INC. (US) 1976-04-27 US disclosed
US-3931151-A ANTIDEPRESSANT, NEURO-SEDATIVE ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed
US-3931193-A ANTIMALARIA, ANTIARRHYTHMIA INTERMEDIATES HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed
US-3931192-A Process for piperidine intermediates for quinine, quinidine and analogs thereof HOFFMANN-LA ROCHE INC. (US) 1976-01-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11638717-B2 Complex of nucleic acid medicine and multibranched lipid FABP1, POLRMT, SREBF1 CYP2C9 4044/4885HPGD 4766/4885MAPK1 4801/4885
US-11845724-B2 USP30 inhibitors and uses thereof USP30, USP28, USP1 CYP2C9 4412/4885HPGD 3509/4885MAPK1 2205/4885
US-20220315531-A1 USP30 INHIBITORS AND USES THEREOF USP30, USP28, USP1 CYP2C9 4412/4885HPGD 3509/4885MAPK1 2205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.