Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL11847430 | 0.94 | — | — | |
| Chloroform SCHEMBL378302 | 0.89 | LMNA (0.33) | — | |
| Chloroform SCHEMBL7930106 | 0.86 | LMNA (0.31) | — | |
| Cyclohexane SCHEMBL8471239 | 0.86 | ADH1C (0.32) | HRH3 | |
| Chloroform SCHEMBL83188 | 0.83 | CYP2C9 (0.32) | — | |
| Cyclohexane SCHEMBL7124692 | 0.83 | HRH3 (0.32) | HRH3 | |
| Fluoride SCHEMBL6463523 | 0.82 | ADH1C (0.31) | HRH3 | |
| Chloroform SCHEMBL2007196 | 0.80 | CYP1A2 (0.31) | — | |
| Chloroform SCHEMBL537028 | 0.80 | ALDH1A1 (0.40) | — | |
| Benzene SCHEMBL11096471 | 0.80 | SIGMAR1 (0.38) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4737505-A | Analgesic 4-substituted indoles | ROUSSEL UCLAF (FR) | 1988-04-12 | — | — | US | disclosed |
| US-4493836-A | HYPOTENSIVE, ANTISEROTONINE AGENTS, DOPAMINE ANTAGONIST | Uclaf, Roussel (FR) | 1985-01-15 | — | — | US | disclosed |
| US-4435408-A | Dopaminergic stimulating and antianoxic 4-substituted 2H-indole-2-ones | ROUSSEL UCLAF (FR) | 1984-03-06 | — | — | US | disclosed |
| US-4382942-A | ANTIEMETICS, PARKINSON*S DISEASE | ROUSSEL UCLAF (FR) | 1983-05-10 | — | — | US | disclosed |
| US-4332808-A | Dopaminergically stimulating 4-substituted indoles | ROUSSEL UCLAF (FR) | 1982-06-01 | — | — | US | disclosed |
| US-4313944-A | Cycloheptindoles, compositions and use | ROUSSEL UCLAF (FR) | 1982-02-02 | — | — | US | disclosed |
| US-4259337-A | ANTIDEPRESSANTS, ANOREXIGENIC AGENTS ANTIPARKINSONIAN ACTIVITY | ROUSSEL UCLAF (FR) | 1981-03-31 | — | — | US | disclosed |
| US-4224333-A | Antihypertensive 2H-indol-2-ones | ROUSSEL UCLAF (FR) | 1980-09-23 | — | — | US | disclosed |
| US-4213989-A | 3-TRIFLUOROMETHYL GROUP ON PHENYL | ROUSSEL UCLAF (FR) | 1980-07-22 | — | — | US | disclosed |
| US-4072685-A | HYPOTENSIVE AGENTS | ROUSSEL UCLAF (FR) | 1978-02-07 | — | — | US | disclosed |
| US-4046901-A | HYPOTENSIVE AGENTS | ROUSSEL-UCLAF (FR) | 1977-09-06 | — | — | US | disclosed |
| US-3979515-A | THYMOANALEPTIC ACTIVITY | ROUSSEL-UCLAF (FR) | 1976-09-07 | — | — | US | disclosed |
| US-3957757-A | THYMOANALEPTICS | ROUSSEL-UCLAF (FR) | 1976-05-18 | — | — | US | disclosed |
| US-3931151-A | ANTIDEPRESSANT, NEURO-SEDATIVE | ROUSSEL-UCLAF (FR) | 1976-01-06 | — | — | US | disclosed |