Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.31 |
| ▸ | FOS | P01100 | 1/20 | 0.31 |
| ▸ | JUN | P05412 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3785121 | 0.88 | MAPT (0.45) | MAPTL3MBTL1AKR1C3ALDH1A1 | |
| SCHEMBL3791372 | 0.87 | MAPT (0.36) | MAPTLMNAL3MBTL1AKR1C3GSK3B | |
| SCHEMBL4643859 | 0.75 | CYP2C19 (0.36) | LMNAL3MBTL1GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL3780762 | 0.74 | MAPT (0.47) | MAPTAKR1C3ALDH1A1PPARG | |
| SCHEMBL3780444 | 0.74 | MAPT (0.47) | MAPTAKR1C3ALDH1A1PPARG | |
| SCHEMBL4643590 | 0.74 | CYP2C19 (0.35) | MAPTLMNAL3MBTL1GSK3BALDH1A1 | |
| SCHEMBL4647347 | 0.74 | ALDH1A1 (0.36) | LMNAL3MBTL1GSK3BALDH1A1SMN1; SMN2 | |
| SCHEMBL475824 | 0.73 | LMNA (0.48) | MAPTLMNASTAT3ALDH1A1SMN1; SMN2 | |
| SCHEMBL4644558 | 0.72 | L3MBTL1 (0.36) | LMNAL3MBTL1GSK3BALDH1A1CYP2C19 | |
| SCHEMBL4642549 | 0.71 | L3MBTL1 (0.35) | LMNAL3MBTL1GSK3BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100183540-A1 | BRANCHED POLYMER AND ANTIFOULING COATING COMPOSITION COMPRISING THE POLYMER | JOTUN A/S (NO) | 2010-07-22 | — | — | US | disclosed |