Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | LMNA | P02545 | 7/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4642549 | 0.86 | L3MBTL1 (0.35) | ALDH1A1LMNASMN1; SMN2CYP2C19CES2 | |
| SCHEMBL4643859 | 0.83 | CYP2C19 (0.36) | ALDH1A1LMNASMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL4644326 | 0.83 | L3MBTL1 (0.37) | ALDH1A1LMNASMN1; SMN2HTTCYP2C19 | |
| SCHEMBL4643870 | 0.82 | L3MBTL1 (0.36) | ALDH1A1LMNARAB9ATDP1L3MBTL1 | |
| SCHEMBL4643590 | 0.81 | CYP2C19 (0.35) | ALDH1A1LMNASMN1; SMN2RAB9ACYP2C19 | |
| SCHEMBL4641979 | 0.81 | ALDH1A1 (0.42) | ALDH1A1LMNASMN1; SMN2HTTRAB9A | |
| SCHEMBL4644558 | 0.80 | L3MBTL1 (0.36) | ALDH1A1LMNACYP2C19CES2CES1 | |
| SCHEMBL4645473 | 0.79 | L3MBTL1 (0.35) | ALDH1A1LMNASMN1; SMN2CYP2C19CES2 | |
| SCHEMBL475824 | 0.76 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2HTTRAB9A | |
| SCHEMBL4642332 | 0.76 | FBP1 (0.36) | ALDH1A1RAB9ACYP2C19TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |