SCHEMBL3783532

SCHEMBL3783532

CCOC(=O)N(C(=O)OCC)c1ccc2cc1-2.OBO

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
RARA P10276 2/20 0.33
RARB P10826 2/20 0.33
RARG P13631 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
PRKCI P41743 1/20 0.33
PRKCZ Q05513 1/20 0.33
POLB P06746 1/20 0.33
HSD17B10 Q99714 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
TSHR P16473 1/20 0.33
HPGD P15428 1/20 0.32
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3784766 0.73 MEN1 (0.37) KMT2AMEN1ALDH1A1LMNAPOLB
SCHEMBL3785829 0.71 RARA (0.39) RARARARBRARGALDH1A1PGR
SCHEMBL3781111 0.70 ALDH1A1 (0.49) KMT2AMEN1ALDH1A1LMNAPOLB
SCHEMBL3781710 0.68 GAA (0.34) KMT2AALDH1A1TSHRPGR
SCHEMBL3783945 0.68 ALDH1A1 (0.37) KMT2AMEN1ALDH1A1LMNAL3MBTL1
SCHEMBL7531399 0.67 CA1 (0.50) KMT2AMEN1ALDH1A1LMNAPOLB
SCHEMBL9770254 0.67 PDCD1 (0.41) KMT2ALMNAL3MBTL1TSHR
SCHEMBL5214499 0.65 RXRA (0.39) RARARARBRARGALDH1A1LMNA
SCHEMBL11400006 0.64 RAB9A (0.49) KMT2AMEN1ALDH1A1LMNAPOLB
SCHEMBL2590921 0.62 KDM4E (0.33) ALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 KMT2A 1474/4885MEN1 174/4885RARA 3419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.