SCHEMBL3789140

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1444778	0.89	TDP1 (0.57)	TDP1MAPK1ALDH1A1CYP3A4APP
	SCHEMBL453782	0.89	TDP1 (0.56)	TDP1MAPK1ALDH1A1CYP3A4APP
	Hydrochloric Acid SCHEMBL6574161	0.87	ALDH1A1 (0.57)	TDP1MAPK1ALDH1A1CYP3A4APP
	SCHEMBL1578362	0.85	MEN1 (0.50)	MAPK1ALDH1A1CYP3A4CYP1A2CYP2D6
	SCHEMBL21708253	0.85	RELA (0.55)	ALDH1A1CYP3A4APPCYP1A2CYP2D6
	SCHEMBL28113571	0.85	HDAC3 (0.49)	TDP1MAPK1ALDH1A1CYP3A4SMN1; SMN2
	SCHEMBL29492486	0.85	ALDH1A1 (0.50)	MAPK1ALDH1A1CYP3A4SMN1; SMN2CYP1A2
	SCHEMBL3785577	0.85	ALDH1A1 (0.50)	MAPK1ALDH1A1CYP3A4SMN1; SMN2CYP1A2
	SCHEMBL3794745	0.85	TDP1 (0.56)	TDP1MAPK1ALDH1A1CYP3A4APP
	SCHEMBL11004268	0.83	ALDH1A1 (0.61)	TDP1MAPK1ALDH1A1CYP3A4APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.