Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9790975 | 0.77 | KMT5A (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM2 | |
| SCHEMBL4798583 | 0.74 | USP30 (0.38) | — | |
| SCHEMBL4887983 | 0.74 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM2 | |
| SCHEMBL652131 | 0.72 | HTT (0.32) | — | |
| SCHEMBL3364565 | 0.72 | HTT (0.32) | — | |
| SCHEMBL2413966 | 0.72 | HCRTR1 (0.45) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM1 | |
| SCHEMBL652986 | 0.72 | HTT (0.32) | — | |
| SCHEMBL20521054 | 0.71 | — | — | |
| SCHEMBL25426783 | 0.69 | HSD11B1 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM2 | |
| SCHEMBL25429104 | 0.69 | HSD11B1 (0.41) | CHRNB2CHRNB4CHRNA3CHRNA4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111057-A1 | NOVEL AMINOPYRIDINE DERIVATIVES HAVING AURORA A SELECTIVE INHIBITORY ACTION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-09-30 | — | — | WO | disclosed |