Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3773379 | 0.78 | — | — | |
| SCHEMBL9246674 | 0.75 | THRB (0.35) | TSHR | |
| SCHEMBL912511 | 0.68 | — | — | |
| SCHEMBL435510 | 0.68 | CD81 (0.31) | — | |
| SCHEMBL2786782 | 0.65 | OPRM1 (0.33) | — | |
| SCHEMBL1552116 | 0.63 | OPRM1 (0.36) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL4794587 | 0.62 | AKR1C1 (0.31) | — | |
| SCHEMBL8573142 | 0.62 | OPRM1 (0.33) | — | |
| SCHEMBL7698928 | 0.61 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL3379293 | 0.61 | TSHR (0.40) | CHRM2CHRM4CHRM5CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8404265-B2 | Contact lenses for extended release of bioactive agents containing diffusion attenuators | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20100330146-A1 | CONTACT LENSES FOR EXTENDED RELEASE OF BIOACTIVE AGENTS CONTAINING DIFFUSION ATTENUATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC. (US) | 2010-12-30 | — | — | US | disclosed |