SCHEMBL3789689

SCHEMBL3789689

Nc1ccc(-c2ccccc2)cc1F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HSD17B10 Q99714 2/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 1/20 0.52
USP2 O75604 1/20 0.52
LMNA P02545 1/20 0.52
HSP90AA1 P07900 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
HPGD P15428 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
HTT P42858 1/20 0.52
IKBKB O14920 1/20 0.50
MAOA P21397 1/20 0.48
TAAR1 Q96RJ0 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
CYP3A4 P08684 1/20 0.48
HDAC2 Q92769 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18560686 1.00 ALDH1A1 (0.52) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL29924944 0.88 ALDH1A1 (0.62) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL1099003 0.88 ALDH1A1 (0.62) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL22360500 0.85 MEN1 (0.53) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL3823490 0.84 ALDH1A1 (0.65) ALDH1A1HSD17B10MEN1KMT2AALOX15
SCHEMBL3790335 0.84 KIF11 (0.59) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL30758809 0.84 KIF11 (0.59) ALDH1A1HSD17B10MEN1KMT2AMAPT
SCHEMBL3787627 0.83 MAOA (0.56) ALDH1A1MEN1KMT2AMAOATAAR1
SCHEMBL22035759 0.82 HSD17B10 (0.57) ALDH1A1HSD17B10MEN1KMT2AKDM4E
SCHEMBL3790222 0.82 HSD17B10 (0.57) ALDH1A1HSD17B10MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109762026-B Fluorine-containing phenanthrenequinone skeleton asymmetric alpha-diimine nickel (II) complex and preparation method and application thereof 常州大学 2021-03-02 CN claimed
CN-109762026-A A kind of fluorine-containing phenanthrenequione skeleton asymmetry alpha-diimine nickel (II) complex and preparation method and application 常州大学 2019-05-17 CN claimed
WO-2025100475-A1 COMPOSITION FOR IMAGE RECORDING AND METHOD FOR PRODUCING SAME キヤノン株式会社 2025-05-15 WO disclosed
EP-3912983-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-11-15 EP disclosed
EP-3851443-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-13 EP disclosed
US-11555012-B2 ACLY inhibitors and uses thereof Nimbus Artemis, Inc. (US) 2023-01-17 US disclosed
EP-4026839-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2022-07-13 EP disclosed
EP-3715437-B1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-01 EP disclosed
EP-3715436-B1 COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2021-12-01 EP disclosed
CN-109704987-B Method for synthesizing 2-fluorobenzene amine compound 浙江工业大学 2021-10-15 CN disclosed
EP-3851443-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-07-21 EP disclosed
CN-105992767-A Wnt pathway modulators 新加坡科技研究局 2016-10-05 CN disclosed
WO-2015187094-A1 PHTHALIMIDE DERIVATIVES AS MODULATORS OF WNT PATHWAY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-12-10 WO disclosed
WO-2015187094-A1 PHTHALIMIDE DERIVATIVES AS MODULATORS OF WNT PATHWAY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-12-10 WO disclosed
WO-2015094118-A1 MALEIMIDE DERIVATIVES AS MODULATORS OF WNT PATHWAY AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-06-25 WO disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1773768-A4 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2008-08-06 EP disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
EP-1773768-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS Exelixis, Inc. (US) 2007-04-18 EP disclosed
WO-2006012642-A2 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS, INC. (US) 2006-02-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 ALDH1A1 4339/4885HSD17B10 1100/4885MEN1 174/4885
US-11555012-B2 ACLY inhibitors and uses thereof ACLY, ATP5ME, ATP5MG ALDH1A1 1455/4885HSD17B10 392/4885MEN1 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.