Water

Water

SCHEMBL3790782

O.[KH].[SiH4]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL21247123 1.00
Water SCHEMBL28471138 0.87
SCHEMBL1812664 0.82
Water SCHEMBL3819207 0.82
Water SCHEMBL251541 0.82
Water SCHEMBL8369534 0.82
Water SCHEMBL8466165 0.82
Water SCHEMBL2355026 0.82
SCHEMBL9764917 0.82
Water SCHEMBL22588912 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118325093-A Method for preparing raw phenyl silicone rubber by one-pot method 江西蓝星星火有机硅有限公司 2024-07-12 CN claimed
CN-117777447-A Method for preparing methyl phenyl silicone oil by one-pot method 江西蓝星星火有机硅有限公司 2024-03-29 CN claimed
CN-115260500-B Acrylate-terminated silicone oil and preparation method thereof 深圳市康利邦科技有限公司 2023-09-29 CN claimed
CN-113698606-B Preparation method of vinyl silicone oil with low content of cyclic bodies 湖北兴瑞硅材料有限公司 2023-03-24 CN claimed
CN-114293319-A Preparation method of low-adsorption ABS plastic material 苏州新华美塑料有限公司 2022-04-08 CN claimed
CN-112608475-A Preparation method of vinyl silicone oil with low hydroxyl content 湖北兴瑞硅材料有限公司 2021-04-06 CN claimed
CN-105489599-B Global illuminating formula LED filament 重庆信德电子有限公司 2019-01-22 CN claimed
CN-107936252-A A kind of reaction system for preparing silicone oil and the method that silicone oil is prepared using the system 江西蓝星星火有机硅有限公司 2018-04-20 CN claimed
CN-104327268-B Siloxane copolymer containing ethyl phenyl silica chain links and preparation method thereof 杭州师范大学 2017-05-10 CN claimed
CN-105552193-A LED filament preparation method Chongqing xinde electronic co ltd 2016-05-04 CN claimed
CN-105542693-A Packaging material for LED filament Chongqing xinde electronic co ltd 2016-05-04 CN claimed
CN-105489599-A All-angle illuminating LED lamp filament Chongqing xinde electronic co ltd 2016-04-13 CN claimed
CN-105111445-A Methyl phenyl silicone oil for LED (light emitting diode) potting sealant and preparation method thereof GUILIN JIANPING ENVIRONMENT PROT & ENERGY ECONOMY CO LTD 2015-12-02 CN claimed
CN-103254434-B High temperature resistant phenyl polysiloxane, compound and preparation method of high temperature resistant phenyl polysiloxane SHANGHAI ASIBO ORGANOSILICON MATERIAL CO LTD 2015-07-15 CN claimed
CN-103275325-B Borosiloxane and preparation method thereof SHANGHAI AISHIBO ORGANOSILICON MATERIAL CO LTD 2015-06-17 CN claimed
CN-104327268-A Siloxane copolymer containing ethyl phenyl silica chain links and preparation method thereof UNIV HANGZHOU NORMAL 2015-02-04 CN claimed
CN-103275325-A Borosiloxane and preparation method thereof SHANGHAI AISHIBO ORGANOSILICON MATERIAL CO LTD 2013-09-04 CN claimed
US-7029830-B2 Precision and apertures for lithographic systems INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2006-04-18 US claimed
CN-118325093-A Method for preparing raw phenyl silicone rubber by one-pot method 江西蓝星星火有机硅有限公司 2024-07-12 CN disclosed
US-4965221-A Spacer isolation method for minimizing parasitic sidewall capacitance and creating fully recessed field oxide regions MICRON TECHNOLOGY, INC. (US) 1990-10-23 US disclosed