Water

Water

SCHEMBL8466165

O.O.O.O.O.O.O.O.O.O.[KH]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL9484116 1.00
Water SCHEMBL8369534 1.00
Water SCHEMBL1504321 1.00
Water SCHEMBL3820520 1.00
Water SCHEMBL22588912 1.00
Water SCHEMBL1530181 1.00
Water SCHEMBL8193216 1.00
Water SCHEMBL6228132 1.00
Water SCHEMBL3819207 1.00
Water SCHEMBL797313 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108963290-A A kind of improvement Cathodic Composition for lifesaving positioning lamp 埃普希勒电动燃料有限公司 2018-12-07 CN claimed
EP-0891224-B1 A METHOD OF PREPARING A VINYL ACETATE CATALYST EMPLOYING AN ALKALI METAL BORATE HOECHST CELANESE CORP (US) 1999-11-24 EP claimed
CN-103069632-B Flow battery system APPLIED MATERIALS, INC. (US) 2015-11-25 CN disclosed
CN-103069632-A Flow battery system APPLIED MATERIALS INC 2013-04-24 CN disclosed
CN-1210390-C Laundry detergent compositions with linea amine based polymer to provide appearance and integrity benefits to fabrics laundered therewith PROCTER & GAMBLE (US) 2005-07-13 CN disclosed
CN-1192086-C Laundry detergent compositions containing anionically modified cyclic amine based polymers PROCTER & GAMBLE (US) 2005-03-09 CN disclosed
CN-1101463-C Process for preparing granular detergent component or composition PROCTER & GAMBLE (US) 2003-02-12 CN disclosed
CN-1346400-A granular detergent composition with improved solubility PROCTER & GAMBLE (US) 2002-04-24 CN disclosed
CN-1320159-A Granular detergent composition having improved appearance and solubility PROCTER & GAMBLE (US) 2001-10-31 CN disclosed
CN-1278296-A Laundry detergent compositions with anionically modified, cyclic amine based polymers PROCTER & GAMBLE (US) 2000-12-27 CN disclosed
CN-1278295-A Laundry detergent compositions containing linear amine based polymers to improve the appearance and integrity of laundered fabrics PROCTER & GAMBLE (US) 2000-12-27 CN disclosed
CN-1045988-C Process for making compact detergent compositions PROCTER & GAMBLE (US) 1999-10-27 CN disclosed
CN-1188505-A Process for preparing granular detergent component or composition PROCTER & GAMBLE (US) 1998-07-22 CN disclosed
CN-1185804-A Bleaching compositions comprising selective perfumes for masking bleach odor PROCTER & GAMBLE (US) 1998-06-24 CN disclosed
CN-1153525-A laundry detergent composition PROCTER & GAMBLE (US) 1997-07-02 CN disclosed
CN-1083521-A The preparation method of compact detergent compositions PROCTER & GAMBLE (US) 1994-03-09 CN disclosed