Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KDM5A | P29375 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | AOC2 | O75106 | 1/20 | 0.51 |
| ▸ | OGG1 | O15527 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25700071 | 0.92 | ALDH1A1 (0.68) | ALDH1A1KDM4EHDAC8NPC1RAB9A | |
| SCHEMBL28254875 | 0.92 | ALDH1A1 (0.68) | ALDH1A1KDM4EHDAC8NPC1RAB9A | |
| SCHEMBL315040 | 0.91 | HDAC8 (0.70) | ALDH1A1KDM4EHDAC8EPHX2NR1H4 | |
| SCHEMBL1904111 | 0.86 | ALDH1A1 (0.70) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL1706875 | 0.84 | NPC1 (0.67) | ALDH1A1KDM4EHDAC8CTDSP1NPC1 | |
| SCHEMBL752600 | 0.84 | MPO (0.70) | ALDH1A1KDM4ECTDSP1NPC1RAB9A | |
| SCHEMBL3370418 | 0.83 | MAPK14 (0.48) | ALDH1A1KDM4EHDAC8CTDSP1NPC1 | |
| Hydrochloric Acid SCHEMBL5804936 | 0.82 | NPC1 (0.64) | ALDH1A1KDM4EHDAC8CTDSP1NPC1 | |
| SCHEMBL17044693 | 0.82 | MPO (0.61) | ALDH1A1KDM4ECTDSP1NPC1RAB9A | |
| SCHEMBL77384 | 0.82 | ALDH1A1 (0.76) | ALDH1A1KDM4EHDAC8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | ALDH1A1 4339/4885KDM4E 2606/4885HDAC8 1421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.