Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3789293 | 0.89 | NAMPT (0.42) | NAMPTMEN1KMT2ALMNAMAPT | |
| SCHEMBL3797563 | 0.87 | NAMPT (0.43) | NAMPTMEN1KMT2ALMNAMAPT | |
| SCHEMBL3789575 | 0.86 | ALDH1A1 (0.40) | NAMPTMEN1KMT2ALMNAMAPT | |
| SCHEMBL13257863 | 0.86 | AKT1 (0.37) | NAMPTTGFBR1MEN1KMT2AGPR139 | |
| SCHEMBL3785444 | 0.80 | NAMPT (0.44) | NAMPTMEN1KMT2ALMNAMAPT | |
| SCHEMBL3788636 | 0.78 | EPHX2 (0.48) | GPR139HDAC1HDAC6 | |
| SCHEMBL13258013 | 0.76 | DRD2 (0.38) | NAMPTMEN1KMT2ASMN1; SMN2HDAC1 | |
| SCHEMBL13258147 | 0.73 | LMNA (0.41) | NAMPTMEN1KMT2ALMNAHTT | |
| SCHEMBL3790162 | 0.70 | EPHX2 (0.51) | GPR139 | |
| SCHEMBL3788746 | 0.70 | EPHX2 (0.45) | NAMPTGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |
| WO-2010096722-A1 | 3-OXO-2, 3-DIHYDRO- [1,2, 4] TRIAZOLO [4, 3-A]PYRIDINES AS SOLUBLE EPOXIDE HYDROLASE (SEH) INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-26 | — | — | WO | disclosed |