Phosphoric Acid

Phosphoric Acid

SCHEMBL3799894

CON1C(C)(C)CC(NC(C)=O)CC1(C)C.O=P(O)(O)O.[KH]

nearest known ligand 0.34

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
GAA P10253 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 2/20 0.32
ATM Q13315 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MEN1 O00255 1/20 0.30
PKM P14618 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL3801972 0.98 KDM4E (0.35) KDM4EGAASMN1; SMN2KMT2AATM
Phosphoric Acid SCHEMBL3801977 0.98 KDM4E (0.35) KDM4EGAASMN1; SMN2KMT2AATM
SCHEMBL18217967 0.92 SMN1; SMN2 (0.36) KDM4EGAASMN1; SMN2KMT2AATM
Phosphoric Acid SCHEMBL3799902 0.91 KDM4E (0.33) KDM4EGAASMN1; SMN2KMT2ATSHR
SCHEMBL12658905 0.80 SMN1; SMN2 (0.39) KDM4EGAASMN1; SMN2KMT2AATM
SCHEMBL1138474 0.77 TSHR (0.46) KDM4EGAASMN1; SMN2KMT2AATM
SCHEMBL4982955 0.74 ALDH1A1 (0.36) KDM4EGAASMN1; SMN2KMT2AATM
SCHEMBL19424075 0.73 TEAD1 (0.33) KDM4EGAASMN1; SMN2KMT2ATSHR
SCHEMBL20313800 0.73 MTNR1A (0.36) KDM4EGAASMN1; SMN2KMT2AATM
SCHEMBL20313798 0.73 MAOB (0.34) KDM4EGAASMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8216596-B2 4-Hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine, citric acid and a body care product; hindered amine salt compounds provide outstanding protection against light-induced fading BASF SE (DE) 2012-07-10 US claimed
EP-1893169-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CONTAINING STERICALLY HINDERED AMINE SALT COMPOUND Ciba Specialty Chemicals Holding Inc. (CH) 2008-03-05 EP claimed
US-20060262149-A1 Ink jet ink and recording material WOOD MERVIN G 2006-11-23 US claimed
US-20060264345-A1 Stabilized body care products, household products, textiles and fabrics BASF SE (DE) 2006-11-23 US claimed
WO-2006122889-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CONTAINING STERICALLY HINDERED AMINE SALT COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-23 WO claimed
WO-2006122888-A1 INK JET INK AND RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-23 WO claimed
EP-2207522-B1 PERSONAL CARE AND HOUSEHOLD PRODUCT COMPOSITIONS COMPRISING SPECIFIC SULFUR CONTAINING STABILISER COMPOUNDS BASF SE (DE) 2019-11-06 EP disclosed
US-8216596-B2 4-Hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine, citric acid and a body care product; hindered amine salt compounds provide outstanding protection against light-induced fading BASF SE (DE) 2012-07-10 US disclosed
EP-2207522-A2 BODY-CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS COMPRISING SPECIFIC SULFUR-CONTAINING COMPOUNDS BASF SE (DE) 2010-07-21 EP disclosed
WO-2009047150-A2 BODY-CARE AND HOUSEHOLD PRODUCTS AND COMPOSITIONS COMPRISING SPECIFIC SULFUR-CONTAINING COMPOUNDS BASF SE (CH) 2009-04-16 WO disclosed
US-20090092561-A1 Body-care and household products and compositions comprising specific sulfur-containing compounds BASF SE (DE) 2009-04-09 US disclosed
EP-1893169-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CONTAINING STERICALLY HINDERED AMINE SALT COMPOUND Ciba Specialty Chemicals Holding Inc. (CH) 2008-03-05 EP disclosed
US-20060262149-A1 Ink jet ink and recording material WOOD MERVIN G 2006-11-23 US disclosed
WO-2006122888-A1 INK JET INK AND RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-23 WO disclosed
US-20060264345-A1 Stabilized body care products, household products, textiles and fabrics BASF SE (DE) 2006-11-23 US disclosed
WO-2006122889-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CONTAINING STERICALLY HINDERED AMINE SALT COMPOUNDS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060264345-A1 Stabilized body care products, household products, textiles and fabrics DSC1, CUTA, DSG1 KDM4E 1172/4885GAA 1243/4885SMN1; SMN2 282/4885
US-20090092561-A1 Body-care and household products and compositions comprising specific sulfur-containing compounds DSC1, SCLY, DSG1 KDM4E 2059/4885GAA 1217/4885SMN1; SMN2 566/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.