Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392030 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL18613882 | 0.77 | CA1 (0.34) | TSHRCA1CA2CA7CA14 | |
| SCHEMBL5872376 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL10496811 | 0.77 | TSHR (0.33) | TSHR | |
| SCHEMBL4654398 | 0.77 | TSHR (0.39) | TSHR | |
| SCHEMBL3064643 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL9229146 | 0.73 | TSHR (0.36) | TSHR | |
| SCHEMBL9938412 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL10372952 | 0.73 | TSHR (0.31) | TSHR | |
| SCHEMBL11720174 | 0.73 | CA2 (0.38) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100298328-A1 | 1-Heterocyclylamino-2-Hydroxy-3-Amino-Omega-Arylalkanes | VITAE PHARMACEUTICALS, INC | 2010-11-25 | — | — | US | claimed |
| WO-2007123718-A1 | 1-HETEROCYCLYLAMINO-2-HYDROXY-3-AMINO-ω-ARYLALKANES | VITAE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | claimed |
| US-20100298328-A1 | 1-Heterocyclylamino-2-Hydroxy-3-Amino-Omega-Arylalkanes | VITAE PHARMACEUTICALS, INC | 2010-11-25 | — | — | US | disclosed |
| WO-2007123718-A1 | 1-HETEROCYCLYLAMINO-2-HYDROXY-3-AMINO-ω-ARYLALKANES | VITAE PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | WO | disclosed |
| US-6911303-B2 | Light-sensitive silver halide grain | FUJI PHOTO FILM, CO., LTD. (JP) | 2005-06-28 | — | — | US | disclosed |
| US-20030186179-A1 | Light-sensitive silver halide grain | FUJI PHOTO FILM CO., LTD. | 2003-10-02 | — | — | US | disclosed |
| US-6413709-B1 | SILVER HALIDE EMULSION DISPERSION | FUJI PHOTO FILM CO., LTD. (JP) | 2002-07-02 | — | — | US | disclosed |
| EP-0573649-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0572662-B1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO LTD (JP) | 1999-03-17 | — | — | EP | disclosed |
| US-5561033-A | SUBJECTING SILVER HALIDE EMULSION TO TELLURIUM SENSITIZATION | FUJI PHOTO FILM, CO., LTD. (JP) | 1996-10-01 | — | — | US | disclosed |
| EP-0573649-A1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-15 | — | — | EP | disclosed |
| EP-0572662-A1 | SILVER HALIDE PHOTOGRAPHIC MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-4804654-A | INSECTICIDES, MITICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298328-A1 | 1-Heterocyclylamino-2-Hydroxy-3-Amino-Omega-Arylalkanes | REN, AGTR1, AGTR2 | TSHR 3735/4885CA1 4781/4885CA2 2137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.