Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8587610 | 0.87 | HCRTR1 (0.57) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL28992535 | 0.82 | HCRTR1 (0.62) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL1006864 | 0.79 | HCRTR1 (0.58) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL18224473 | 0.77 | HCRTR1 (0.57) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL6589832 | 0.77 | HCRTR1 (0.57) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL28373054 | 0.77 | HCRTR1 (0.50) | HCRTR1ESR1ESR2L3MBTL1ALDH1A1 | |
| SCHEMBL28026700 | 0.75 | KMT2A (0.51) | NPSR1L3MBTL1ALDH1A1MAPTHTT | |
| SCHEMBL6464181 | 0.75 | HCRTR1 (0.62) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL4282830 | 0.75 | HCRTR1 (0.62) | HCRTR1NPSR1ESR1ESR2L3MBTL1 | |
| SCHEMBL28213609 | 0.75 | ADRB2 (0.52) | NPSR1L3MBTL1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | TECHFIELDS PHARMA CO., LTD. (CN) | 2009-09-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238763-A1 | HIGH PENETRATION COMPOSITIONS AND USES THEREOF | HPGDS, PTGIS, PTGES | HCRTR1 1930/4885NPSR1 205/4885ESR1 2142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.