Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3817549 | 0.88 | NPC1 (0.39) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL3814741 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL3809475 | 0.85 | TP53 (0.43) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL3812671 | 0.82 | ALOX15 (0.41) | ALDH1A1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL3812645 | 0.81 | MAPT (0.43) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL3814874 | 0.80 | LTB4R2 (0.40) | ALDH1A1RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL3807301 | 0.79 | GSTO1 (0.35) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL2158566 | 0.77 | ALDH1A1 (0.40) | ALDH1A1HTTNPSR1MEN1KMT2A | |
| SCHEMBL3811085 | 0.76 | NR1H4 (0.41) | MEN1KMT2ARAB9AOPRM1 | |
| SCHEMBL3812570 | 0.76 | LTB4R2 (0.39) | HTTRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401825-B1 | THIOPHENE DERIVATIVES AS ANTIVIRAL AGENTS FOR FLAVIVIRUS INFECTION | VIROCHEM PHARMA INC (CA) | 2009-08-05 | — | — | EP | claimed |