Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MMP13 | P45452 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | GFER | P55789 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.55 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3815151 | 0.90 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL17905725 | 0.84 | EPHX2 (0.69) | ALDH1A1SMN1; SMN2HTTMMP13EPHX2 | |
| SCHEMBL22221566 | 0.83 | EPHX2 (0.71) | ALDH1A1SMN1; SMN2HTTMMP13EPHX2 | |
| SCHEMBL13853495 | 0.82 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL26051502 | 0.82 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL23771131 | 0.81 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL4892249 | 0.81 | FBP1 (0.53) | ALDH1A1SMN1; SMN2MMP13LMNAMAPT | |
| SCHEMBL13251391 | 0.81 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL13272298 | 0.80 | MTNR1A (0.58) | ALDH1A1SMN1; SMN2HTTMMP13LMNA | |
| SCHEMBL4893863 | 0.80 | EPHX1 (0.49) | LMNAMAPTALOX15KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557853-B2 | Aryl fluoroethyl ureas acting as alpha 2 adrenergic agents | ALLERGAN, INC. (US) | 2013-10-15 | — | — | US | disclosed |
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ALLERGHAN, INC. | 2008-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194650-A1 | ARYL FLUOROETHYL UREAS ACTING AS ALPHA 2 ADRENERGIC AGENTS | ADRB2, ADRA2C, ADRA2A | ALDH1A1 389/4885SMN1; SMN2 2419/4885HTT 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.