Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | GLS | O94925 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118247 | 0.71 | HSD17B10 (0.53) | ALDH1A1KDM4EHSD17B10ALOX15MAPT | |
| SCHEMBL8871239 | 0.60 | NOS3 (0.33) | — | |
| SCHEMBL15772874 | 0.60 | HSD17B10 (0.52) | ALDH1A1KDM4EHSD17B10ALOX15APOBEC3G | |
| SCHEMBL23635739 | 0.60 | MAPT (0.33) | ALDH1A1MAPTLMNA | |
| SCHEMBL4394601 | 0.59 | ALDH1A1 (0.31) | ALDH1A1KDM4EL3MBTL1LMNA | |
| SCHEMBL8673328 | 0.58 | — | — | |
| SCHEMBL5039837 | 0.58 | CASP1 (0.38) | ALDH1A1KDM4EHSD17B10ALOX15MAPT | |
| SCHEMBL147208 | 0.58 | — | — | |
| SCHEMBL17427791 | 0.58 | MEN1 (0.42) | ALDH1A1KDM4EHSD17B10ALOX15MAPT | |
| SCHEMBL23097832 | 0.58 | ALDH1A1 (0.33) | ALDH1A1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233998-B1 | SILICONE COMPOSITIONS FOR PERSONAL CARE PRODUCTS AND METHODS FOR MAKING | MOMENTIVE PERFORMANCE MAT INC (US) | 2009-08-05 | — | — | EP | disclosed |
| EP-1172398-B1 | Silicone compositions for personal care products and method for making | GEN ELECTRIC (US) | 2007-04-04 | — | — | EP | disclosed |
| US-6849265-B2 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-6849264-B2 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2005-02-01 | — | — | US | disclosed |
| US-6844002-B2 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-6841164-B2 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2005-01-11 | — | — | US | disclosed |
| US-6752984-B2 | FOR HAIR CONDITIONING | GENERAL ELECTRIC COMPANY | 2004-06-22 | — | — | US | disclosed |
| US-20030103928-A1 | Silicone compositions for personal care products and method for making | MOMENTIVE PERFORMANCE MATERIALS INC. | 2003-06-05 | — | — | US | disclosed |
| EP-1172411-B1 | Silicone compositions for personal care products and method of manufacture | GEN ELECTRIC (US) | 2003-06-04 | — | — | EP | disclosed |
| US-20030095939-A1 | Silicone connected to a heterocyclic trimethylpyrimidinium compound through a linker to improve adhesion to fibers such as hair and textiles. | MOMENTIVE PERFORMANCE MATERIALS INC. | 2003-05-22 | — | — | US | disclosed |
| US-20030086891-A1 | Silicone compositions for personal care products and method for making | MOMENTIVE PERFORMANCE MATERIALS INC. | 2003-05-08 | — | — | US | disclosed |
| US-6506371-B1 | Polysiloxane linked to such as a quaternary pyridinium, triazinium, pyrimidinium or pyrazine group; durable treatment of damaged hair | GENERAL ELECTRIC COMPANY | 2003-01-14 | — | — | US | disclosed |
| US-6488921-B1 | HAIR CONDITIONERS; POLYSILOXANE OR SILICONE RESIN, AT LEAST ONE LINKER, AND AT LEAST ONE MOLECULAR HOOK THAT COMPROMISES A HETEROCYCLIC TRIMETHYLPYRIMIDINIUM COMPOUND | GENERAL ELECTRIC COMPANY | 2002-12-03 | — | — | US | disclosed |
| EP-1233998-A1 | SILICONE COMPOSITIONS FOR PERSONAL CARE PRODUCTS AND METHODS FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2002-08-28 | — | — | EP | disclosed |
| US-6390102-B1 | HAIR COSMETIC | GENERAL ELECTRIC COMPANY | 2002-05-21 | — | — | US | disclosed |
| WO-2002006382-A1 | SILICONE COMPOSITIONS FOR PERSONAL CARE PRODUCTS AND METHODS FOR MAKING | GENERAL ELECTRIC COMPANY (US) | 2002-01-24 | — | — | WO | disclosed |
| EP-1172398-A2 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-1172411-A1 | Silicone compositions for personal care products and method for making | GENERAL ELECTRIC COMPANY (US) | 2002-01-16 | — | — | EP | disclosed |
| EP-0431331-B1 | THERMOSETTING MIXTURES OF MATERIALS | BASF Aktiengesellschaft (DE) | 1993-05-05 | — | — | EP | disclosed |
| EP-0431331-A1 | Thermosetting mixtures of materials | BASF Aktiengesellschaft (DE) | 1991-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030095939-A1 | Silicone connected to a heterocyclic trimethylpyrimidinium compound through a linker to improve adhesion to fibers such as hair and textiles. | SMC4, VIM, SMC2 | ALDH1A1 3385/4885KDM4E 466/4885HSD17B10 3233/4885 |
| US-20030103928-A1 | Silicone compositions for personal care products and method for making | TERT, KAT7, TERB1 | ALDH1A1 4678/4885KDM4E 772/4885HSD17B10 3539/4885 |
| US-20030086891-A1 | Silicone compositions for personal care products and method for making | TERT, KAT7, TERB1 | ALDH1A1 4678/4885KDM4E 772/4885HSD17B10 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.