Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14275214 | 0.88 | MAPT (0.34) | KDM1AALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL31207773 | 0.86 | MEN1 (0.41) | KDM1AALDH1A1HPGDDRD4LMNA | |
| SCHEMBL31207785 | 0.75 | HTR6 (0.38) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL5061808 | 0.74 | GFER (0.43) | LMNAPRKCZNPC1MAPT | |
| SCHEMBL31207784 | 0.73 | LMNA (0.41) | ALDH1A1HPGDKDM4ELMNAMEN1 | |
| SCHEMBL31263067 | 0.70 | ALDH1A1 (0.36) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL31478293 | 0.69 | KDM1A (0.52) | KDM1AALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL10287802 | 0.68 | ALDH1A1 (0.38) | ALDH1A1HPGDDRD4DRD2KMT2A | |
| SCHEMBL7991481 | 0.67 | MAPT (0.45) | ALDH1A1HPGDKDM4ELMNAPOLB | |
| SCHEMBL22906223 | 0.65 | L3MBTL1 (0.38) | ALDH1A1HPGDKDM4ELMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140210-A2 | RADIOTRACERS FOR IMAGING CANNABINOID SUB-TYPE1 (CB1) RECEPTOR | THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-11-19 | — | — | WO | disclosed |