SCHEMBL381772

SCHEMBL381772

NCCN[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GGT1 P19440 1/20 0.56
CPB2 Q96IY4 5/20 0.41
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CPB1 P15086 1/20 0.39
MME P08473 2/20 0.39
GABRR1 P24046 2/20 0.38
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
FOLH1 Q04609 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL692576 1.00 GGT1 (0.56) GGT1CPB2CA2CA4CPB1
SCHEMBL7091886 1.00 GGT1 (0.56) GGT1CPB2CA2CA4CPB1
Water SCHEMBL25415254 0.98 GGT1 (0.55) GGT1CPB2CA2CA4CPB1
SCHEMBL1446361 0.98 GGT1 (0.55) GGT1CPB2CA2CA4CPB1
Ethylenediamine SCHEMBL8741929 0.91 GGT1 (0.47) GGT1CA2CA4GABRR1LMNA
SCHEMBL30370036 0.88 GGT1 (0.46) GGT1CPB2CA2CA4MME
SCHEMBL30437177 0.88 GGT1 (0.46) GGT1CPB2CA2CA4MME
SCHEMBL30436578 0.88 GGT1 (0.46) GGT1CPB2CA2CA4MME
SCHEMBL30437179 0.88 GGT1 (0.46) GGT1CPB2CA2CA4MME
SCHEMBL7861449 0.88 GGT1 (0.46) GGT1CPB2CA2CA4MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2920249-B1 SELF-DISPERSING PIGMENTS CHEMOURS CO FC LLC (US) 2020-04-01 EP claimed
US-10316209-B2 Self-dispersing pigments THE CHEMOURS COMPANY FC, LLC (US) 2019-06-11 US claimed
CN-104937040-B Self-dispersing pigment 纳幕尔杜邦公司 2017-11-21 CN claimed
CN-104919007-B Self-dispersing pigments comprising silica 纳幕尔杜邦公司 2017-09-26 CN claimed
US-20150307683-A1 SILICA CONTAINING SELF-DISPERSING PIGMENTS E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-29 US claimed
US-20150291822-A1 SELF-DISPERSING PIGMENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2015-10-15 US claimed
CN-104937040-A Self-dispersing pigments DU PONT 2015-09-23 CN claimed
CN-104919007-A Self-dispersing pigments comprising silica DU PONT 2015-09-16 CN claimed
US-7442788-B2 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2008-10-28 US claimed
US-6872809-B2 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2005-03-29 US claimed
US-20030208050-A1 Nucleoside derivatives JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-11-06 US claimed
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-08-28 US claimed
EP-1295892-A1 ANTISENSE MOLECULES AND METHOD OF CONTROLLING EXPRESSION OF GENE FUNCTION BY USING THE SAME Japan Science and Technology Corporation (JP) 2003-03-26 EP claimed
EP-1295891-A1 NUCLEOSIDE DERIVATIVES Japan Science and Technology Corporation (JP) 2003-03-26 EP claimed
CN-116426491-A Preparation method for synthesizing AMA and derivatives thereof by double enzyme coupling 中国药科大学 2023-07-14 CN disclosed
CN-113521272-B Novel coronavirus pneumonia DNA nano vaccine and preparation method thereof 四川大学 2023-05-09 CN disclosed
EP-4160208-A1 URINE SEDIMENT STAINING LIQUID TOYOBO CO., LTD. (JP) 2023-04-05 EP disclosed
EP-1165488-A1 PROCESS FOR THE PREPARATION OF POLYAMINO SUCCINIC ACIDS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 2002-01-02 EP disclosed
WO-2001096355-A1 NUCLEOSIDE DERIVATIVES JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2001-12-20 WO disclosed
WO-2000058263-A1 PROCESS FOR THE PREPARATION OF POLYAMINO SUCCINIC ACIDS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 2000-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030162739-A1 Antisense molecules and method of controlling expression of gene function by using the same RNGTT, RNMT, UPF1 GGT1 2807/4885CPB2 2425/4885CA2 3574/4885
US-20030208050-A1 Nucleoside derivatives RIMKLA, MTHFD1, AADAT GGT1 279/4885CPB2 1928/4885CA2 3081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.