SCHEMBL3818110

SCHEMBL3818110

CC(C)c1cc(-c2ccc(C#N)cc2)[c]c(-c2ccc(C#N)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 3/20 0.39
MMP3 P08254 2/20 0.38
CYP2A6 P11509 2/20 0.38
ALDH1A1 P00352 1/20 0.38
GRIA1 P42261 1/20 0.37
GRIA2 P42262 1/20 0.37
GRIA3 P42263 1/20 0.37
GRIA4 P48058 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.36
SCN10A Q9Y5Y9 1/20 0.35
ERBB2 P04626 1/20 0.35
MAOB P27338 1/20 0.35
XDH P47989 1/20 0.35
KDM1A O60341 1/20 0.34
CA12 O43570 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
ABCC9 O60706 1/20 0.33
KCNJ11 Q14654 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3817728 0.81 CYP2C9 (0.38) KIF11ALDH1A1ERBB2GAA
SCHEMBL24017151 0.79 KIF11 (0.47) KIF11MMP3CYP2A6ALDH1A1GRIA1
SCHEMBL12263202 0.77 MMP3 (0.52) KIF11MMP3CYP2A6ALDH1A1GRIA1
SCHEMBL3819329 0.76 RXRA (0.42) ALDH1A1HSD17B10GAA
SCHEMBL840282 0.75 METAP2 (0.40) KIF11ALDH1A1TSHR
SCHEMBL87339 0.74 CYP2A6 (0.52) KIF11CYP2A6ALDH1A1GRIA1GRIA2
SCHEMBL24726522 0.71 RXRA (0.54) KIF11MMP3GRIA1GRIA2GRIA3
SCHEMBL23625544 0.71 CYP11B2 (0.43) KIF11MMP3ALDH1A1GRIA1GRIA2
SCHEMBL10880463 0.71 TTR (0.42) CYP2A6ALDH1A1ERBB2CA12CA2
SCHEMBL3818485 0.71 KIF11 (0.39) KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US claimed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US claimed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US claimed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP claimed
US-11404650-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-08-02 US disclosed
US-10381579-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-13 US disclosed
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-09-03 US disclosed
CN-101180304-B Stable OLED materials and devices with improved stability UNIVERSAL DISPLAY CORP. (US) 2015-08-19 CN disclosed
US-9051344-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-06-09 US disclosed
US-7902374-B2 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2011-03-08 US disclosed
EP-1878053-B1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORP (US) 2009-08-26 EP disclosed
WO-2008054584-A1 IMPROVED STABILITY OLED MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2008-05-08 WO disclosed
EP-1878053-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY Universal Display Corporation (US) 2008-01-16 EP disclosed
US-20070088167-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2007-04-19 US disclosed
WO-2006121811-A1 STABILITY OLED MATERIALS AND DEVICES WITH IMPROVED STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2006-11-16 WO disclosed
US-20060251923-A1 Stability OLED materials and devices UNIVERSAL DISPLAY CORPORATION 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11404650-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 KIF11 2643/4885MMP3 3568/4885CYP2A6 2520/4885
US-10381579-B2 Stability OLED materials and devices OCIAD2, OCIAD1, OSBP2 KIF11 2666/4885MMP3 3579/4885CYP2A6 2453/4885
US-20150249225-A1 STABILITY OLED MATERIALS AND DEVICES OCIAD2, OCIAD1, OSBP2 KIF11 2666/4885MMP3 3579/4885CYP2A6 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.