Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31370923 | 0.83 | ACHE (0.48) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL38658816 | 0.81 | CYP1A2 (0.32) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL4696476 | 0.79 | TAAR1 (0.47) | CYP1A2ALDH1A1CA1CA2CA7 | |
| SCHEMBL2093321 | 0.77 | CYP1A2 (0.43) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL2927525 | 0.75 | ALDH1A1 (0.54) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL770140 | 0.75 | CYP1A2 (0.47) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL22280009 | 0.74 | CYP1A2 (0.41) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL1006539 | 0.73 | CYP1A2 (0.45) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| Ethylene SCHEMBL25437125 | 0.71 | TRPA1 (0.55) | CYP1A2CYP2A6TSHRACHEALDH1A1 | |
| SCHEMBL9644071 | 0.71 | CYP1A2 (0.43) | CYP1A2CYP2A6TSHRACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106278898-B | A kind of peptide condensation reagent 3 ', 5 '-bis trifluoromethyl biphenyl -3,5- iodosobenzen ediacetates and preparation method thereof | 南开大学 | 2018-10-30 | — | — | CN | claimed |
| CN-105566162-B | The preparation technology of rilpivirine intermediate | 苏州莱克施德药业有限公司 | 2017-11-03 | — | — | CN | claimed |
| CN-106278898-A | A kind of peptide condensation reagent 3 ', 5 '-bis trifluoromethyl biphenyl-3,5-iodosobenzen ediacetate and preparation method thereof | 南开大学 | 2017-01-04 | — | — | CN | claimed |
| CN-102558241-B | Preparation of 1,10-phenanthroline complex substituted by propionyl group and application of complex used as catalyst | CHINA PETROLEUM & CHEMICAL | 2014-11-26 | — | — | CN | claimed |
| CN-102532201-B | Preparation of formoxyl substitutional 1, 10-phenanthroline coordination compound and application of prepared coordination compound as catalyst | CHINA PETROLEUM & CHEMICAL | 2014-11-05 | — | — | CN | claimed |
| CN-102558242-B | Preparation of isobutyryl substituted 1,10-phenanthroline complex and application of complex serving as catalyst | SINOPEC CORP. (CN) | 2014-10-22 | — | — | CN | claimed |
| CN-102558243-B | Preparation method of alkyl-substituted 1,10-phenanthroline complex and application of complex prepared thereby as catalyst | SINOPEC CORP. (CN) | 2014-10-22 | — | — | CN | claimed |
| CN-103804428-A | Preparation method and application of complex | CHINA PETROLEUM & CHEMICAL | 2014-05-21 | — | — | CN | claimed |
| CN-110352195-A | Catalyst | 博里利斯股份公司 | 2019-10-18 | — | — | CN | disclosed |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | APALENE TECHNOLOGY CO., LTD. (HANGZHOU) (CN) | 2019-10-15 | — | — | US | disclosed |
| CN-110177798-A | Catalyst | 博里利斯股份公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-106278898-B | A kind of peptide condensation reagent 3 ', 5 '-bis trifluoromethyl biphenyl -3,5- iodosobenzen ediacetates and preparation method thereof | 南开大学 | 2018-10-30 | — | — | CN | disclosed |
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | APALENE TECHNOLOGY CO., LTD. (JIAXING) (CN) | 2018-05-31 | — | — | US | disclosed |
| CN-107799658-A | Light-emitting component, light-emitting device, electronic equipment, lighting device and organometallic complex | 株式会社半导体能源研究所 | 2018-03-13 | — | — | CN | disclosed |
| CN-102775539-B | Preparation method of polybutadiene | CHANGCHUN APPLIED CHEMISTRY | 2014-03-26 | — | — | CN | disclosed |
| CN-101970572-B | Photocurable composition | SEKISUI CHEMICAL CO LTD | 2014-01-29 | — | — | CN | disclosed |
| CN-102134214-B | Isoindolone compounds and their use as metabotropic glutamate receptor potentiators | ASTRAZENECA AB | 2013-05-22 | — | — | CN | disclosed |
| WO-2009120826-A1 | 2-ARYL- AND 2-HETEROARYLTHIAZOLYL COMPOUNDS, METHODS FOR THEIR PREPARATION AND USE THEREOF | WYETH (US) | 2009-10-01 | — | — | WO | disclosed |
| EP-2089384-A2 | 2-(PIPERIDIN-4-YL)-4-PHENOXY-OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. Hoffmann-Roche AG (CH) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008071587-A2 | 2-(PIPERIDIN-4-YL)-4-PHENOXY- OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147571-A1 | NOVEL LINEAR ALPHA-OLEFIN CATALYSTS AND PREPARATION AND USE THEREOF | UBE2L3, RNF168, AGL | CYP1A2 2080/4885CYP2A6 2658/4885TSHR 2124/4885 |
| US-10441946-B2 | Linear alpha-olefin catalysts and preparation and use thereof | UBE2L3, COG8, ACSL3 | CYP1A2 1760/4885CYP2A6 2553/4885TSHR 2300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.