Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 5/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3830568 | 0.98 | TKT (0.36) | TKTAOC1AOC3KCNH2TMEM97 | |
| SCHEMBL3821718 | 0.83 | TKT (0.39) | TKTKCNH2TMEM97SIGMAR1 | |
| SCHEMBL3825476 | 0.81 | TKT (0.41) | TKT | |
| SCHEMBL3825587 | 0.79 | LMNA (0.40) | TKTAOC1AOC3TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3825409 | 0.78 | LMNA (0.39) | AOC1AOC3 | |
| SCHEMBL3821791 | 0.73 | AOC1 (0.36) | AOC1AOC3 | |
| SCHEMBL31583156 | 0.70 | CNR2 (0.36) | TKTKCNH2TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3830563 | 0.68 | PIM1 (0.35) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL29156171 | 0.68 | TDO2 (0.37) | — | |
| SCHEMBL19359654 | 0.67 | AOC1 (0.48) | AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096111-A1 | PYRAZOLES AND USE THEREOF AS DRUGS | Japan Tobacco Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | JAPAN TOBACCO, INC. (JP) | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036450-A1 | PYRAZOLE COMPOUNDS AND USE THEREOF | PYGL, GYS2, G6PC1 | TKT 852/4885AOC1 2879/4885AOC3 2549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.