SCHEMBL3821674

SCHEMBL3821674

C=CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.71
▸ POLB P06746 1/20 0.71
▸ TGM2 P21980 2/20 0.71
▸ KMT2A Q03164 5/20 0.60
▸ LMNA P02545 4/20 0.60
▸ MEN1 O00255 4/20 0.60
▸ SMN1; SMN2 Q16637 2/20 0.60
▸ ALOX12 P18054 1/20 0.60
▸ RECQL P46063 1/20 0.60
▸ HSD17B10 Q99714 1/20 0.60
▸ MAPT P10636 4/20 0.60
▸ HPGD P15428 2/20 0.60
▸ HDAC4 P56524 2/20 0.59
▸ HDAC1 Q13547 2/20 0.59
▸ GLA P06280 1/20 0.59
▸ CRHBP P24387 1/20 0.59
▸ HTT P42858 1/20 0.59
▸ CRHR2 Q13324 1/20 0.59
▸ HDAC8 Q9BY41 1/20 0.59
▸ SNCA P37840 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9568792 1.00 ALDH1A1 (0.71) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL3820009 0.87 TGM2 (0.67) ALDH1A1POLBTGM2KMT2AMEN1
SCHEMBL19457348 0.86 TGM2 (0.77) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL9568733 0.86 BTK (0.63) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL14394824 0.86 ALDH1A1 (0.65) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL14394819 0.85 CES1 (0.65) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL17240362 0.85 TGM2 (0.57) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL9568604 0.85 TGM2 (0.64) ALDH1A1POLBTGM2KMT2AMEN1
SCHEMBL23988634 0.85 TGM2 (0.58) ALDH1A1POLBTGM2KMT2ALMNA
SCHEMBL648950 0.84 TGM2 (1.00) ALDH1A1POLBTGM2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048981-B1 Methode for negative type image recording FUJIFILM CORP (JP) 2009-08-19 — — EP disclosed
EP-1219464-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2008-02-13 — — EP disclosed
US-6890700-B2 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJI PHOTO FILM CO., LTD. (JP) 2005-05-10 — — US disclosed
EP-1078736-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-01-28 — — EP disclosed
EP-0854388-B1 Negative-type image recording materials FUJI PHOTO FILM CO LTD (JP) 2003-08-13 — — EP disclosed
US-20020182538-A1 Capable of plate-making by scanning exposure based on digital signals, high sensitivity, free of residual color and residual film phenomena, and excellent in resistance to smearing (i.e., staining) and excellent in press life FUJIFILM CORPORATION (JP) 2002-12-05 — — US disclosed
US-6416939-B1 EXPOSURE, HEATING AND DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 2002-07-09 — — US disclosed
EP-1219464-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2002-07-03 — — EP disclosed
US-6238839-B1 DIMENSIONALLY STABLE METAL SUPPORT COATED WITH A HEAT-INSULATING LAYER, A HYDROPHILIC LAYER AND A THERMOSENSITIVE LIPOPHILIC LAYER; IMAGE QUALITY, MULTICOLOR PRINTS FUJI PHOTO FILM CO., LTD. (JP) 2001-05-29 — — US disclosed
EP-1078736-A1 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2001-02-28 — — EP disclosed
EP-1048981-A1 Negative type image recording material FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 — — EP disclosed
US-6068963-A CONTAINS (A) A POLYMER HAVING A HETEROCYCLIC GROUP CONTAINING AN UNSATURATED BOND THEREIN, (B) A CROSS-LINKING AGENT THAT CROSS-LINKS WITH THE AID OF AN ACID, AND (C) A COMPOUND THAT GENERATES AN ACID UPON EXPOSURE TO LIGHT OR HEAT. FUJI PHOTO FILM CO., LTD. (JP) 2000-05-30 — — US disclosed
EP-0854388-A2 Negative-type image recording materials FUJI PHOTO FILM CO., LTD. (JP) 1998-07-22 — — EP disclosed
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